Recombinant Human CHTOP Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CHTOP-3945H
• Product Overview: C1orf77 MS Standard C13 and N15-labeled recombinant protein (NP_056422) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a small nuclear protein that is characterized by an arginine and glycine rich region. This protein may have an important role in the regulation of fetal globin gene expression and in the activation of estrogen-responsive genes. A recent study reported that this protein binds 5-hydroxymethylcytosine (5hmC) and associates with an arginine methyltransferase complex (methylosome), which promotes methylation of arginine 3 of histone H4 (H4R3) and activation of genes involved in glioblastomagenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 26.5 kDa
• AA Sequence: MAAQSAPKVVLKSTTKMSLNERFTN MLKNKQPTPVNIRASMQQQQQLASA RNRRLAQQMENRPSVQAALKLKQKS LKQRLGKSNIQARLGRPIGALARGA IGGRGLPIIQRGLPRGGLRGGRATR TLLRGGMSLRGQNLLRGGRAVAPRM GLRRGGVRGRGGPGRGGLGRGAMGR GGIGGRGRGMIGRGRGGFGGRGRGR GRGRGALARPVLTKEQLDNQLDAYM SKTKGHLDAELDAYMAQTDPETNDT RTRPLEQKLISEEDLAANDILDYKD DDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CHTOP chromatin target of PRMT1 [ Homo sapiens (human) ]
• Official Symbol: CHTOP
• Synonyms: CHTOP; chromatin target of PRMT1; C1orf77, chromosome 1 open reading frame 77; chromatin target of PRMT1 protein; DKFZP547E1010; FOP; Friend of Prmt1; small protein rich in arginine and glycine; SRAG; friend of PRMT1 protein; SRAG-3; SRAG-5; pp7704; C1orf77; FL-SRAG; RP1-178F15.2; FLJ40551; MGC86949; MGC131924; DKFZp547E1010
• Gene ID: 26097
• mRNA Refseq: NM_015607
• Protein Refseq: NP_056422
• MIM: 614206
• UniProt ID: Q9Y3Y2