Recombinant Human CLDN18 protein, His-tagged

• Cat.No.: CLDN18-856H
• Product Overview: Human Claudin 18.2 is expressed from E.coli with a 6-His tag at the C-terminal. It contains Met27-Arg80 & Val136-Ala 184.

Specification

• Description: Claudin18(CLDN18) belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. CLDN18 is specifically expressed in the stomach and lung. CLDN18 has two alternatively spliced variants,CLDN18.1 and CLDN18.2. Isoform 2 (Claudin 18.2) is abundant in gastric tumors.
• Source: E.coli
• Species: Human
• Tag: His
• Form: Supplied as 0.22um filtered solution in 10mM Na2CO3-NaHCO3 and 5% glycerol (pH 10.0).
• Molecular Mass: The protein has a predicted MW of 31.6 kDa same as Bis-Tris PAGE result.
• Protein length: Met27-Arg80 & Val136-Ala 184
• Endotoxin: Less than 1EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: CLDN18 claudin 18 [ Homo sapiens (human) ]
• Official Symbol: CLDN18
• Synonyms: CLDN18, CLDN18.2, Claudin-18.2
• Gene ID: 51208
• mRNA Refseq: NM_001002026.3
• Protein Refseq: NP_001002026.1
• MIM: 609210
• UniProt ID: P56856