Recombinant Human CLEC4M Protein, His-tagged
Cat.No. : | CLEC4M-007H |
Product Overview : | Recombinant Human CLEC4M Protein with His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Dendritic cells (DC) are antigen-presenting immune system cells that are present on peripheral mucosal tissues and migrate to lymphoid tissues. DC-SIGN (DC-specific ICAM-3 grabbing nonintegrin) is a type II membrane protein that is exclusively expressed by DC. DC-SIGN, also designated CD209, binds to ICAM-3 to mediate the initial interaction between DC and resting T cells through the immunological synapse. The DC that are present in the initial sites of HIV-1 infection capture HIV-1 through DC-SIGN, which then facilitates the migration of DC to areas of T cell-rich secondary lymphoid organs, where it promotes efficient trans HIV-1 infection of these T cells. DC-SIGNR (DC-SIGNrelated molecule), also designated CD209L and L-SIGN (liver/lymph nodespecific ICAM-3 grabbing nonintegrin), is a type II integral membrane protein that is 77% identical to DC-SIGN. It is expressed on sinusoidal endothelial cells and binds the E2 glycoproteins of the hepatitis C virus. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | ~38 kDa |
AA Sequence : | MQVSKVPSSLSQEQSEQDAIYQNLT QLKAAVGELSEKSKLQEIYQELTQL KAAVGELPEKSKLQEIYQELTRLKA AVGELPEKSKLQEIYQELTRLKAAV GELPEKSKLQEIYQELTRLKA AVGELPEKSKLQEIYQELTELKAAVGELP EKSKLQEIYQELTQLKAAVGELPDQ SKQQQIYQELTDLKTAFERLCRHCP KDWTFFQGNCYFMSNSQRNWHDSVT ACQEVRAQLVVIKTAEEQNFLQLQT SRSNRFSWMGLSDLNQEGTWQWVDG SPLSPSFQRYWNSGEPNNSGNEDCA EFSGSGWNDNRCDVDNYWICKKPAA CFRDE |
Purity : | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
Notes : | For research use only, not for use in diagnostic procedure. |
Storage : | Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. |
Storage Buffer : | PBS, 4M Urea, pH7.4 |
Gene Name : | CLEC4M C-type lectin domain family 4, member M [ Homo sapiens (human) ] |
Official Symbol : | CLEC4M |
Synonyms : | CLEC4M; C-type lectin domain family 4, member M; CD209L, CD299, CD299 antigen; C-type lectin domain family 4 member M; DC SIGN2; DC SIGNR; DCSIGNR; HP10347; LSIGN; CD299 antigen; DC-SIGN-related protein; CD209 antigen-like protein 1; mannose binding C-type lectin DC-SIGNR; dendritic cell-specific ICAM-3-grabbing non-integrin 2; liver/lymph node-specific ICAM-3 grabbing non-integrin; liver/lymph node-specific ICAM-3-grabbing non-integrin; CD299; CD209L; L-SIGN; DC-SIGN2; DC-SIGNR; MGC47866; MGC129964; |
Gene ID : | 10332 |
mRNA Refseq : | NM_001144904 |
Protein Refseq : | NP_001138376 |
MIM : | 605872 |
UniProt ID : | Q9H2X3 |
Products Types
◆ Recombinant Protein | ||
CLEC4M-179H | Recombinant Human CLEC4M Protein, His (Fc)-Avi-tagged | +Inquiry |
CLEC4M-3264H | Recombinant Human CLEC4M Protein, MYC/DDK-tagged | +Inquiry |
CLEC4M-07H | Recombinant Human CLEC4M Protein, His-tagged | +Inquiry |
CLEC4M-02H | Recombinant Human CLEC4M Protein, hIgG/His-tagged | +Inquiry |
CLEC4M-3263H | Recombinant Human CLEC4M Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
CLEC4M-2744HCL | Recombinant Human CLEC4M cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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