| Description : |
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
59.8 kDa |
| AA Sequence : |
MSWHPQYRSSKFRHVFGKPASKENC YDSVPITRSVHDNHFCAVNPHFIAV VTECAGGGAFLVIPLHQTGKLDPHY PKVCGHRGNVLDVKWNPFDDFEIAS CSEDATIKIWSIPKQLLTRNLTAYR KELVGHARRVGLVEWHPTAANILFS AGYDYKVMIWNLDTKESVITSPMST ISCHQDVILSMSFNTNGSLLATTCK DRKIRVIDPRAGTVLQEASYKGHRA SKVLFLGNLKKLMSTGTSRWNNRQV ALWDQDNLSVPLMEEDLDGSSGVLF PFYDADTSMLYVVGKGDGNIRYYEV SADKPHLSYLTEYRSYNPQKGIGVM PKRGLDVSSCEIFRFYKLITTKSLI EPISMIVPRRSESYQEDIYPPTAGA QPSLTAQEWLSGMNRDPILVSLRPG SELLRPHPLPAERPIFNSMAPASPR LLNQTEKLAAEDGWRSSSLLEEKMP RWAAEHRLEEKKTWLTNGFDVFECP PPKTENELLQMFYRQQEEIRRLREL LTQREVQAKQLELEIKNLRMGSEQL TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
