Recombinant Human CRBN Protein, His-tagged

• Cat.No.: CRBN-09H
• Product Overview: Recombinant Human CRBN Protein, fused to His-tag, was expressed in E. coli.

Specification

• Description: This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 50mM Tris, 0.3 M NaCl, pH 8.0.
• Molecular Mass: 17.6 kDa
• AA Sequence: MHHHHHHHHHHMNKCTSLCCKQCQE TEITTKNEIFSLSLCGPMAAYVNPH GYVHETLTVYKACNLNLIGRPSTEH SWFPGYAWTVAQCKICASHIGWKFT ATKKDMSPQKFWGLTRSALLPTIPD TEDEISPDKVILCLGLNDIFEAQKI EWHE
• Purity: ＞90%
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.4 mg/mL

Gene Information

• Gene Name: CRBN cereblon [ Homo sapiens (human) ]
• Official Symbol: CRBN
• Synonyms: MRT2; MRT2A
• Gene ID: 51185
• mRNA Refseq: NM_016302
• Protein Refseq: NP_057386
• MIM: 609262
• UniProt ID: Q96SW2