Recombinant Human CREBL2 Protein, GST-tagged
Cat.No. : | CREBL2-1854H |
Product Overview : | Human CREBL2 full-length ORF ( NP_001301.1, 1 a.a. - 120 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 40.2 kDa |
AA Sequence : | MDDSKVVGGKVKKPGKRGRKPAKID LKAKLERSRQSARECRARKKLRYQY LEELVSSRERAICALREELEMYKQW CMAMDQGKIPSEIKALLTGEEQNKS QQNSSRHTKAGKTDANSNSW |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CREBL2 cAMP responsive element binding protein-like 2 [ Homo sapiens ] |
Official Symbol : | CREBL2 |
Synonyms : | CREBL2; cAMP responsive element binding protein-like 2; cAMP-responsive element-binding protein-like 2; MHBs-binding protein 1; MGC117311; MGC138362; |
Gene ID : | 1389 |
mRNA Refseq : | NM_001310 |
Protein Refseq : | NP_001301 |
MIM : | 603476 |
UniProt ID : | O60519 |
Products Types
◆ Recombinant Protein | ||
CREBL2-848R | Recombinant Rhesus Macaque CREBL2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CREBL2-1969M | Recombinant Mouse CREBL2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CREBL2-1250R | Recombinant Rat CREBL2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CREBL2-1023R | Recombinant Rhesus monkey CREBL2 Protein, His-tagged | +Inquiry |
CREBL2-5373C | Recombinant Chicken CREBL2 | +Inquiry |
◆ Lysates | ||
CREBL2-398HCL | Recombinant Human CREBL2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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