Recombinant Human Crystallin, Gamma C, His-tagged
Cat.No. : | CRYGC-2396H |
Product Overview : | Recombinant humanCRYGC protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques |
- Specification
- Gene Information
- Related Products
Cat. No. : | CRYGC-2396H |
Description : | Gamma-crystallin C, alsoknown as CRYGC, belongs to the beta/gamma-crystallin family. Mammalian lenscrystallins are divided into alpha, beta, and gamma families; beta and gammacrystallins are also considered as a superfamily. Gamma-crystallins are ahomogeneous group of highly symmetrical, monomeric proteins typically lackingconnecting peptides and terminal extensions. They are differentiallyregulated after early development. Four gamma-crystallin genes (gamma-Athrough gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) areorganized in a genomic segment as a gene cluster. Whether due to aging ormutations in specific genes, gamma-crystallins have been involved in cataractformation. Defects in CRYGC are a cause of cataract autosomal dominant (ADC)and cataract Coppock-like (CCL) |
Form : | Liquid. In 20 mMTris-HCl buffer, pH8.0, 10% glycerol, 2mM DTT, 200mM NaCl |
Molecular Weight : | 23.5kDa (198aa),confirmed by MALDI-TOF |
Purity : | > 95% by SDS -PAGE |
Concentration : | 1mg/ml (determinedby Bradford assay) |
Sequences of aminoacids : | MGSSHHHHHHSSGLVPRGSH MGSHMGKITF YEDRAFQGRS YETTTDCPNL QPYFSRCNSI RVESGCWMLY ERPNYQGQQYLLRRGEYPDY QQWMGLSDSI RSCCLIPQTV SHRLRLYERE DHKGLMMELS EDCPSIQDRF HLSEIRSLHVLEGCWVLYEL PNYRGRQYLL RPQEYRRCQD WGAMDAKAGS LRRVVDLY |
Storage : | Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene name : | CRYGCcrystallin, gamma C [ Homo sapiens ] |
Official Symbol : | CRYGC |
Synonyms : | CRYGC; crystallin, gamma C; CRYG3; gamma-crystallin C; CATARACT,VARIABLE ZONULAR PULVERULENT; CCL; CRGC_HUMAN; CRYG 3; Cryg 5; Cryg; CRYG3;CRYGC; Crystallin gamma 3; Crystallin gamma C; Gamma C crystallin; Gammacrystallin 2 1; Gamma crystallin 3; Gamma crystallin C; Gamma-C-crystallin;Gamma-crystallin 2-1; Gamma-crystallin 3; Gamma-crystallin C; Gammab cry;Len; OTTHUMP00000163869; gamma-C-crystallin; gamma-crystallin 3; crystallin,gamma-3; gamma-crystallin 2-1; CCL; |
Gene ID : | 1420 |
mRNA Refseq : | NM_020989 |
Protein Refseq : | NP_066269 |
Uniprot ID : | P07315 |
Chromosome Location : | 2q33-q35 |
Function : | protein binding; structural constituent of eye lens |
Products Types
◆ Recombinant Protein | ||
CRYGC-1276R | Recombinant Rat CRYGC Protein, His (Fc)-Avi-tagged | +Inquiry |
CRYGC-869R | Recombinant Rhesus Macaque CRYGC Protein, His (Fc)-Avi-tagged | +Inquiry |
CRYGC-1939H | Recombinant Human CRYGC Protein, GST-tagged | +Inquiry |
CRYGC-1618R | Recombinant Rat CRYGC Protein | +Inquiry |
CRYGC-27305TH | Recombinant Human CRYGC | +Inquiry |
◆ Lysates | ||
CRYGC-7258HCL | Recombinant Human CRYGC 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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