Recombinant Human CSNK1G2 Protein (K5-D353), His tagged
Cat.No. : | CSNK1G2-1191H |
Product Overview : | Recombinant Human 6His-TEV-CK1g(K5-D353) Protein was expressed in Insect cell. |
- Specification
- Gene Information
- Related Products
Description : | Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation. |
Source : | Insect cell |
Species : | Human |
Tag : | His |
Form : | Liquid |
Protein Length : | K5-D353 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | CSNK1G2 casein kinase 1, gamma 2 [ Homo sapiens (human) ] |
Official Symbol : | CSNK1G2 |
Synonyms : | CSNK1G2; casein kinase 1, gamma 2; casein kinase I isoform gamma-2; CK1g2; CKI-gamma 2; casein kinase 1 isoform gamma-2; |
Gene ID : | 1455 |
mRNA Refseq : | NM_001319 |
Protein Refseq : | NP_001310 |
MIM : | 602214 |
UniProt ID : | P78368 |
Products Types
◆ Recombinant Protein | ||
CSNK1G2-1999H | Active Recombinant Human CSNK1G2 Protein, GST-tagged | +Inquiry |
CSNK1G2-1293R | Recombinant Rat CSNK1G2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CSNK1G2-2000H | Recombinant Human CSNK1G2 Protein, GST-tagged | +Inquiry |
CSNK1G2-1190H | Recombinant Human CSNK1G2 Protein (K5-D353), Tag Free | +Inquiry |
CSNK1G2-2021M | Recombinant Mouse CSNK1G2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CSNK1G2-597HCL | Recombinant Human CSNK1G2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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