Recombinant Human CTSB Protein, GST-tagged
Cat.No. : | CTSB-2099H |
Product Overview : | Human CTSB full-length ORF ( AAH10240, 21 a.a. - 339 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein has been associated with esophageal adenocarcinoma and other tumors. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Nov 2015] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 60.72 kDa |
AA Sequence : | PSFHPVSDELVNYVNKRNTTWQAGH NFYNVDMGYLKRLCGTFLGGPKPPQ RVMFTEDLKLPASFDAREQWPQCPT IKEIRDQGSCGSCWAFGAVEAISDR ICIHTNAHVSVEVSAEDLLTCCGSM CGDGCNGGYPAEAWNFWTRKGLVSG GLYESHVGCRPYSIPPCEHHVNGSR PPCTGEGDTPKCSKICEPGYSPTYK QDKHYGYNSYSVSNSEKDIMAEIYK NGPVEGAFSVYSDFLLYKSGVYQHV TGEMMGGHAIRILGWGVENGTPYWL VANSWNTDWGDNGFFKILRGQDHCG IESEVVAGIPRTDQYWEKI |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CTSB cathepsin B [ Homo sapiens ] |
Official Symbol : | CTSB |
Synonyms : | CTSB; cathepsin B; cathepsin B1; APP secretase; cysteine protease; amyloid precursor protein secretase; APPS; CPSB; |
Gene ID : | 1508 |
mRNA Refseq : | NM_001908 |
Protein Refseq : | NP_001899 |
MIM : | 116810 |
UniProt ID : | P07858 |
Products Types
◆ Recombinant Protein | ||
Ctsb-10530M | Recombinant Mouse Ctsb Protein, His (Fc)-Avi-tagged | +Inquiry |
CTSB-3369H | Recombinant Human CTSB Protein, MYC/DDK-tagged | +Inquiry |
Ctsb-2367M | Recombinant Mouse Ctsb Protein, Myc/DDK-tagged | +Inquiry |
CTSB-911R | Recombinant Rhesus Macaque CTSB Protein, His (Fc)-Avi-tagged | +Inquiry |
CTSB-175C | Recombinant Cynomolgus Monkey CTSB Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
CTSB-188B | Active Native Bovine Cathepsin B | +Inquiry |
CTSB-5328H | Native Human Cathepsin B | +Inquiry |
CTSB-26408TH | Native Human CTSB | +Inquiry |
◆ Lysates | ||
CTSB-3025HCL | Recombinant Human CTSB cell lysate | +Inquiry |
CTSB-1885MCL | Recombinant Mouse CTSB cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2366 | Cathepsin B (CTSB) Inhibitor Screening Kit (Fluorometric) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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