Recombinant Human CTSD, His-tagged, C13&N15 Labeled
Cat.No. : | CTSD-207H |
Product Overview : | Recombinant Human CTSD MS Standard Protein, C13 and N15-labeled (CTSD / Cathepsin D, Heavy Labeled) Ser 19 - Leu 412 (Accession # NP_001900) was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain >99% incorpor |
- Specification
- Gene Information
- Related Products
Description : | Cathepsin D is also known as CTSD, CPSD, which belongs to the peptidase A1 family. Cathepsin D can be cleaved into the following 2 chains: cathepsin D light chain and cathepsin D heavy chain, which is expressed in the aorta extrcellular space (at protein level). The catalytic activity of Cathepsin D is specificity similar to, but narrower than, that of pepsin A. Cathepsin D does not cleave the 4-Gln-|-His-5 bond in B chain of insulin. Cathepsin D involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Ser 19 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization. |
Molecular Mass : | CTSD / Cathepsin D, Heavy Labeled is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 43.6 kDa. The predicted N-terminus is Ser 19. DTT-reduced Protein migrates as 45-55 kDa in SDS-PAGE due to glycosylation.CTSD / Cathepsin D, |
Endotoxin : | Less than 1.0 EU per μg of the CTSD / Cathepsin D, Heavy Labeled by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Applications : | MS Standard Protein |
Storage : | Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4oC); After reconstitution under sterile conditions for 3 months (-70oC). |
Gene Name : | CTSD cathepsin D [ Homo sapiens ] |
Official Symbol : | CTSD |
Synonyms : | CTSD; cathepsin D; cathepsin D (lysosomal aspartyl protease) , CPSD; ceroid lipofuscinosis; neuronal 10; CLN10; lysosomal aspartyl protease; lysosomal aspartyl peptidase; ceroid-lipofuscinosis, neuronal 10; CPSD; MGC2311; |
Gene ID : | 1509 |
mRNA Refseq : | NM_001909 |
Protein Refseq : | NP_001900 |
MIM : | 116840 |
UniProt ID : | P07339 |
Chromosome Location : | 11p15.5 |
Pathway : | Ceramide signaling pathway, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; LKB1 signaling events, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Tuberculosis, organism-specific biosystem; Tuberculosis, conserved biosystem; |
Function : | aspartic-type endopeptidase activity; peptidase activity; |
Products Types
◆ Recombinant Protein | ||
CTSD-2582H | Recombinant Human CTSD protein(71-410 aa), C-His-tagged | +Inquiry |
CTSD-435C | Recombinant Cricetulus Griseus CTSD Protein (65-408 aa), His-SUMO-tagged | +Inquiry |
CTSD-913R | Recombinant Rhesus Macaque CTSD Protein, His (Fc)-Avi-tagged | +Inquiry |
Ctsd-2369M | Recombinant Mouse Ctsd Protein, His-tagged | +Inquiry |
CTSD-2752H | Recombinant Human CTSD Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
CTSD-189H | Active Native Human Cathepsin D | +Inquiry |
CTSD-27858TH | Native Human CTSD | +Inquiry |
CTSD-1648H | Active Native Human Cathepsin D | +Inquiry |
◆ Lysates | ||
CTSD-3023MCL | Recombinant Mouse CTSD cell lysate | +Inquiry |
CTSD-1735HCL | Recombinant Human CTSD cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0264 | Cathepsin D Inhibitor Screening Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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