| Description : |
This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
43.6 kDa |
| Protein Length : |
412 |
| AA Sequence : |
MQPSSLLPLALCLLAAPASALVRIP LHKFTSIRRTMSEVGGSVEDLIAKG PVSKYSQAVPAVTEGPIPEVLKNYM DAQYYGEIGIGTPPQCFTVVFDTGS SNLWVPSIHCKLLDIACWIHHKYNS DKSSTYVKNGTSFDIHYGSGSLSGY LSQDTVSVPCQSASSASALGGVKVE RQVFGEATKQPGITFIAAKFDGILG MAYPRISVNNVLPVFDNLMQQKLVD QNIFSFYLSRDPDAQPGGELMLGGT DSKYYKGSLSYLNVTRKAYWQVHLD QVEVASGLTLCKEGCEAIVDTGTSL MVGPVDEVRELQKAIGAVPLIQGEY MIPCEKVSTLPAITLKLGGKGYKLS PEDYTLKVSQAGKTLCLSGFMGMDI PPPSGPLWILGDVFIGRYYTVFDRD NNRVGFAEAARL |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
