Recombinant Human CTSL Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | CTSL-4100H |
Product Overview : | CTSL1 MS Standard C13 and N15-labeled recombinant protein (NP_666023) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Additionally, this protein may be necessary for entry of SARS-CoV-2 (COVID-19 virus) into the cell. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 37.5 kDa |
AA Sequence : | MNPTLILAAFCLGIASATLTFDHSL EAQWTKWKAMHNRLYGMNEEGWRRA VWEKNVKMIELHNQEYREGKHSFTM AMNAFGDMTSEEFRQVMNGFQNRKP RKGKVFQEPLFYEAPRSVDWREKGY VTPVKNQGQCGSCWAFSATGALEGQ MFRKTGRLISLSEQNLVDCSGPQGN EGCNGGLMDYAFQYVQDNGGLDSEE SYPYEATEESCKYNPKYSVANDTGF VDIPKQEKALMKAVATVGPISVAID AGHESFLFYKEGIYFEPDCSSEDMD HGVLVVGYGFESTESDNNKYWLVKN SWGEEWGMGGYVKMAKDRRNHCGIA SAASYPTVTRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | CTSL cathepsin L [ Homo sapiens (human) ] |
Official Symbol : | CTSL |
Synonyms : | CTSL; cathepsin L; MEP; CATL; CTSL1; procathepsin L; cathepsin L1; major excreted protein; EC 3.4.22.15 |
Gene ID : | 1514 |
mRNA Refseq : | NM_145918 |
Protein Refseq : | NP_666023 |
MIM : | 116880 |
UniProt ID : | P07711 |
Products Types
◆ Recombinant Protein | ||
CTSL-2113H | Recombinant Human CTSL Protein, GST-tagged | +Inquiry |
CTSL-687H | Recombinant Human CTSL Protein, His (Fc)-Avi-tagged | +Inquiry |
CTSL-120H | Recombinant Human CTSL Protein, His-tagged | +Inquiry |
CTSL-3380H | Recombinant Human CTSL Protein, MYC/DDK-tagged | +Inquiry |
CTSL-2070M | Recombinant Mouse CTSL Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
CTSL-191H | Active Native Human Cathepsin L | +Inquiry |
◆ Lysates | ||
CTSL1-1867MCL | Recombinant Mouse CTSL1 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2351 | Cathepsin L Inhibitor Screening Kit (Fluorometric) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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