Recombinant Human CTTN Protein, DDK-tagged
Cat.No. : |
CTTN-782H |
Product Overview : |
Recombinant Human CTTN, transcript variant 2, fused with DDK tag at C-terminal was expressed in Sf9 cells. |
- Specification
- Gene Information
- Related Products
Description : |
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. |
Source : |
Sf9 cells |
Species : |
Human |
Tag : |
DDK |
Form : |
50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol. |
Molecular Mass : |
57.3 kDa |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : |
>50 ug/mL as determined by microplate BCA method |
Gene Name : |
CTTN cortactin [ Homo sapiens ] |
Official Symbol : |
CTTN |
Synonyms : |
CTTN; cortactin; EMS1, ems1 sequence (mammary tumor and squamous cell carcinoma associated (p80/85 src substrate); src substrate cortactin; amplaxin; 1110020L01Rik; oncogene EMS1; ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate); EMS1; FLJ34459; |
Gene ID : |
2017 |
mRNA Refseq : |
NM_001184740 |
Protein Refseq : |
NP_001171669 |
MIM : |
164765 |
UniProt ID : |
Q14247 |
Products Types
Related Gene
CTTN
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