Recombinant Human CXCL1 Protein, DYKDDDDK-tagged

• Cat.No.: CXCL1-151H
• Product Overview: Recombinant Human chemokine (C-X-C motif) ligand 1(melanoma growth stimulating activity, alpha)(CXCL1), transcript variant 1 (NM_001511), with a DYKDDDDK tag, was expressed in human cells.

Specification

• Description: This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.
• Source: Human Cells
• Species: Human
• Tag: DYKDDDDK
• Form: Purified protein formulated in a sterile solution of TBS buffer, pH7.69, without any preservatives.
• Molecular Mass: 7.8 kDa
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
• Purity: >90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.

Gene Information

• Gene Name: CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) [ Homo sapiens ]
• Official Symbol: CXCL1
• Synonyms: CXCL1; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); fibroblast secretory protein , FSP, GRO1, GRO1 oncogene (melanoma growth stimulating activity, alpha) , MGSA; growth-regulated alpha protein; GROa; MGSA a; NAP 3; SCYB1; MGSA alpha; GRO-alpha(1-73); C-X-C motif chemokine 1; fibroblast secretory protein; neutrophil-activating protein 3; melanoma growth stimulatory activity alpha; GRO1 oncogene (melanoma growth-stimulating activity); GRO1 oncogene (melanoma growth stimulating activity, alpha); FSP; GRO1; MGSA; NAP-3; MGSA-a
• Gene ID: 2919
• mRNA Refseq: NM_001511
• Protein Refseq: NP_001502
• MIM: 155730
• UniProt ID: P09341