Recombinant Human CXCL5 protein, His & GST-tagged
Cat.No. : | CXCL5-7840H |
Product Overview : | Recombinant Human CXCL5 aa. (Gly38~Asn114) fused with N-terminal His & GST tag was produced in E. coli cells. |
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Description : | This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. |
Source : | E. coli |
Species : | Human |
Tag : | His & GST |
Form : | Freeze-dried powder |
Molecular Mass : | 38kDa as determined by SDS-PAGE reducing conditions. |
Protein length : | Gly38~Asn114 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >98% |
Characteristic : | The isoelectric point is 7.2. |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Concentration : | 200μg/mL |
Storage buffer : | 10mM PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and Proclin300. |
Reconstitution : | Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | CXCL5 C-X-C motif chemokine ligand 5 [ Homo sapiens (human) ] |
Official Symbol : | CXCL5 |
Synonyms : | CXCL5; C-X-C motif chemokine ligand 5; SCYB5; ENA-78; C-X-C motif chemokine 5; chemokine (C-X-C motif) ligand 5; epithelial-derived neutrophil-activating protein 78; neutrophil-activating peptide ENA-78; neutrophil-activating protein 78; small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78) |
Gene ID : | 6374 |
mRNA Refseq : | NM_002994.4 |
Protein Refseq : | NP_002985.1 |
UniProt ID : | P42830 |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCXCL5 is implicated in promoting tumor growth and metastasis by facilitating the migration of cancer cells and modulating the tumor microenvironment.
Several clinical trials are exploring the efficacy of drugs that modulate CXCL5 levels in various diseases, including cancer, autoimmune disorders, and inflammatory conditions.
CXCL5 has been identified as a regulator of angiogenesis, influencing the formation of new blood vessels, a process crucial for tumor growth and wound healing.
CXCL5's role in recruiting cells to damaged tissues makes it a potential candidate for enhancing regenerative medicine approaches, such as tissue repair and wound healing.
CXCL5 levels can be measured in blood or tissue samples to assess the extent of inflammation, aiding in the diagnosis and monitoring of various diseases.
Customer Reviews (3)
Write a reviewIts versatility and reliability make it an indispensable asset for scientists seeking to explore the complexities of various biological systems.
Its stability and functional attributes ensure reliable imaging and facilitate the elucidation of complex protein structures.
The CXCL5 protein is known for its exceptional quality, making it a highly suitable choice for meeting diverse experimental needs.
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