Recombinant Human DAAM1 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | DAAM1-2226H |
Product Overview : | DAAM1 MS Standard C13 and N15-labeled recombinant protein (NP_055807) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct proteins. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 123.3 kDa |
AA Sequence : | MAPRKRGGRGISFIFCCFRNNDHPE ITYRLRNDSNFALQTMEPALPMPPV EELDVMFSELVDELDLTDKHREAMF ALPAEKKWQIYCSKKKDQEENKGAT SWPEFYIDQLNSMAARKSLLALEKE EEEERSKTIESLKTALRTKPMRFVT RFIDLDGLSCILNFLKTMDYETSES RIHTSLIGCIKALMNNSQGRAHVLA HSESINVIAQSLSTENIKTKVAVLE ILGAVCLVPGGHKKVLQAMLHYQKY ASERTRFQTLINDLDKSTGRYRDEV SLKTAIMSFINAVLSQGAGVESLDF RLHLRYEFLMLGIQPVIDKLREHEN STLDRHLDFFEMLRNEDELEFAKRF ELVHIDTKSATQMFELTRKRLTHSE AYPHFMSILHHCLQMPYKRSGNTVQ YWLLLDRIIQQIVIQNDKGQDPDST PLENFNIKNVVRMLVNENEVKQWKE QAEKMRKEHNELQQKLEKKERECDA KTQEKEEMMQTLNKMKEKLEKETTE HKQVKQQVADLTAQLHELSRRAVCA SIPGGPSPGAPGGPFPSSVPGSLLP PPPPPPLPGGMLPPPPPPLPPGGPP PPPGPPPLGAIMPPPGAPMGLALKK KSIPQPTNALKSFNWSKLPENKLEG TVWTEIDDTKVFKILDLEDLERTFS AYQRQQDFFVNSNSKQKEADAIDDT LSSKLKVKELSVIDGRRAQNCNILL SRLKLSNDEIKRAILTMDEQEDLPK DMLEQLLKFVPEKSDIDLLEEHKHE LDRMAKADRFLFEMSRINHYQQRLQ SLYFKKKFAERVAEVKPKVEAIRSG SEEVFRSGALKQLLEVVLAFGNYMN KGQRGNAYGFKISSLNKIADTKSSI DKNITLLHYLITIVENKYPSVLNLN EELRDIPQAAKVNMTELDKEISTLR SGLKAVETELEYQKSQPPQPGDKFV SVVSQFITVASFSFSDVEDLLAEAK DLFTKAVKHFGEEAGKIQPDEFFGI FDQFLQAVSEAKQENENMRKKKEEE ERRARMEAQLKEQRERERKMRKAKE NSEESGEFDDLVSALRSGEVFDKDL SKLKRNRKRITNQMTDSSRERPITK LNFTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | DAAM1 dishevelled associated activator of morphogenesis 1 [ Homo sapiens (human) ] |
Official Symbol : | DAAM1 |
Synonyms : | DAAM1; dishevelled associated activator of morphogenesis 1; disheveled-associated activator of morphogenesis 1; KIAA0666; FLJ41657; |
Gene ID : | 23002 |
mRNA Refseq : | NM_014992 |
Protein Refseq : | NP_055807 |
MIM : | 606626 |
UniProt ID : | Q9Y4D1 |
Products Types
◆ Recombinant Protein | ||
DAAM1-989H | Recombinant Human DAAM1 Protein, MYC/DDK-tagged | +Inquiry |
DAAM1-671H | Recombinant Human DAAM1 Protein, His-tagged | +Inquiry |
DAAM1-997R | Recombinant Rhesus Macaque DAAM1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Daam1-2444M | Recombinant Mouse Daam1 Protein, Myc/DDK-tagged | +Inquiry |
DAAM1-2312H | Recombinant Human DAAM1 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
DAAM1-2111HCL | Recombinant Human DAAM1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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