Recombinant Human DAPK3, GST-tagged, Active
Cat.No. : | DAPK3-291H |
Product Overview : | Recombinant human full-length DAPK3 was expressed by baculovirus inSf9 insect cellsusing a N-terminal GST tag. MW= 79kDa. |
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Cat. No. : | DAPK3-291H |
Description : | DAPK3 or Death-associated protein kinase 3 (also known as ZIP) plays a role in apoptosis. DAPK3 is a nuclear serine/threonine-specific kinase that phosphorylates core histones H3 and H4, and myosine light chain in vitro. DAPK3 interacts with transcription and splicing factors as well as with pro-apoptotic protein Par-4 suggesting that it participates in multiple cellular processes. DAPK3 contains a leucine zipper structure at its C terminus and this region is responsible for binding to ATF4. The leucine zipper domain is necessary for the homodimerization of DAPK3 as well as for the activation of the kinase. |
Source : | Sf9 insect cellsusing baculovirus. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | DAPK3 death-associated protein kinase 3 [ Homo sapiens ] |
Synonyms : | DAPK3; death-associated protein kinase 3; ZIP; ZIPK; FLJ36473; ZIP kinase isoform; EC 2.7.11.1; ZIP-kinase |
Gene ID : | 1613 |
mRNA Refseq : | NM_001348 |
Protein Refseq : | NP_001339 |
MIM : | 603289 |
UniProt ID : | O43293 |
Chromosome Location : | 19p13.3 |
Pathway : | Bladder cancer; Pathways in cancer |
Function : | ATP binding; calmodulin binding; nucleotide binding ; protein serine/threonine kinase activity transferase activity |
Products Types
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DAPK3-1002R | Recombinant Rhesus Macaque DAPK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
DAPK3-616HCL | Recombinant Human DAPK3 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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