Recombinant Human DAZ3 Protein, GST-tagged

• Cat.No.: DAZ3-2355H
• Product Overview: Human DAZ3 partial ORF ( NP_065097, 387 a.a. - 438 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 31.46 kDa
• AA Sequence: YPNSAVQVTTGYQFHVYNYQMPPQC PVGEQRRNLWTEAYKWWYLVCLIQR RD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DAZ3 deleted in azoospermia 3 [ Homo sapiens ]
• Official Symbol: DAZ3
• Synonyms: DAZ3; deleted in azoospermia 3; deleted in azoospermia protein 3; pDP1679; MGC126441
• Gene ID: 57054
• mRNA Refseq: NM_020364
• Protein Refseq: NP_065097
• MIM: 400027
• UniProt ID: Q9NR90