Recombinant Human DBH Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | DBH-4346H |
Product Overview : | DBH MS Standard C13 and N15-labeled recombinant protein (NP_000778) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. The encoded protein, expressed in neuroscretory vesicles and chromaffin granules of the adrenal medulla, catalyzes the conversion of dopamine to norepinephrine, which functions as both a hormone and as the main neurotransmitter of the sympathetic nervous system. The enzyme encoded by this gene exists exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. Mutations in this gene cause dopamine beta-hydroxylate deficiency in human patients, characterized by deficits in autonomic and cardiovascular function, including hypotension and ptosis. Polymorphisms in this gene may play a role in a variety of psychiatric disorders. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 69.06 kDa |
AA Sequence : | MPALSRWASLPGPSMREAAFMYSTA VAIFLVILVAALQGSAPRESPLPYH IPLDPEGSLELSWNVSYTQEAIHFQ LLVRRLKAGVLFGMSDRGELENADL VVLWTDGDTAYFADAWSDQKGQIHL DPQQDYQLLQVQRTPEGLTLLFKRP FGTCDPKDYLIXDGTVHLVYGILEE PFRSLEAINGSGLQMGLQRVQLLKP NIPEPELPSDACTMEVQAPNIQIPS QETTYWCYIKELPKGFSRHHIIKYE PIVTKGNEALVHHMEVFQCAPEMDS VPHFSGPCDSKMKPDRLNYCRHVLA AWALGAKAFYYPEEAGLAFGGPGSS RYLRLEVHYHNPLVIEGRNDSSGIR LYYTAKLRRFNAGIMELGLVYTPVM AIPPRETAFILTGYCTDKCTQLALP PSGIHIFASQLHTHLTGRKVVTVLV RDGREWEIVNQDNHYSPHFQEIRML KKVVSVHPGDVLITSCTYNTEDREL ATVGGFGILEEMCVNYVHYYPQTQL ELCKSAVDAGFLQKYFHLINRFNNE DVCTCPQASVSQQFTSVPWNSFNRD VLKALYSFAPISMHCNKSSAVRFQG EWNLQPLPKVISTLEEPTPQCPTSQ GRSPAGPTVVSIGGGKGSGPTRTRR LEQKLISEEDLAANDILDYKDDDDK V |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | DBH dopamine beta-hydroxylase [ Homo sapiens (human) ] |
Official Symbol : | DBH |
Synonyms : | DBH; dopamine beta-hydroxylase (dopamine beta-monooxygenase); dopamine beta-hydroxylase; DBM; |
Gene ID : | 1621 |
mRNA Refseq : | NM_000787 |
Protein Refseq : | NP_000778 |
MIM : | 609312 |
UniProt ID : | P09172 |
Products Types
◆ Recombinant Protein | ||
DBH-2610H | Recombinant Human DBH protein(38-617 aa), C-His-tagged | +Inquiry |
DBH-2122H | Recombinant Human DBH Protein, His-tagged | +Inquiry |
DBH-719H | Recombinant Human DBH Protein, His (Fc)-Avi-tagged | +Inquiry |
DBH-2611H | Recombinant Human DBH protein(41-270 aa), N-MBP & N-His-tagged | +Inquiry |
DBH-2366H | Recombinant Human DBH Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
DBH-869HCL | Recombinant Human DBH cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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