Recombinant Human DCAMKL2, GST-tagged, Active
Cat.No. : | DCAMKL2-293H |
Product Overview : | Recombinant human DCAMKL2 (1-690) was expressed by baculovirus inSf9 insect cellsusing a N-terminal GST tag. MW=105kDa. |
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Cat. No. : | DCAMKL2-293H |
Description : | DCAMKL2 (also known as doublecortin-like kinase 2 or DCLK2) is a close homologue of doublecortin or DCX which is associated with intractable epilepsy in humans, due to a severe disorganization of the neocortex and hippocampus known as classical lissencephaly. DCX; DCLK2-null mice display frequent spontaneous seizures that originate in the hippocampus, with most animals dying in the first few months of life. |
Source : | Sf9 insect cellsusing baculovirus. |
Sequence : | 1-690. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | DCLK2 doublecortin-like kinase 2 [ Homo sapiens ] |
Synonyms : | DCLK2; doublecortin-like kinase 2; CL2, CLICK2, DCAMKL2, DCDC3, DCDC3B, DCK2, DKFZp761I032, MGC45428; doublecortin and CaM kinase-like 2; EC 2.7.11.1 |
Gene ID : | 166614 |
mRNA Refseq : | NM_001040260 |
Protein Refseq : | NP_001035350 |
MIM : | 613166 |
UniProt ID : | Q8N568 |
Chromosome Location : | 4q31.23-q31. |
Pathway : | Bladder cancer; Pathways in cancer |
Function : | ATP binding; nucleotide binding; protein serine/threonine kinase activity transferase activity |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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