Recombinant Human DENND1A Protein, GST-tagged
Cat.No. : | DENND1A-2532H |
Product Overview : | Human DENND1A full-length ORF ( NP_079096.2, 1 a.a. - 559 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 89.8 kDa |
AA Sequence : | MGSRIKQNPETTFEVYVEVAYPRTG GTLSDPEVQRQFPEDYSDQEVLQTL TKFCFPFYVDSLTVSQVGQNFTFVL TDIDSKQRFGFCRLSSGAKSCFCIL SYLPWFEVFYKLLNILADYTTKRQE NQWNELLETLHKLPIPDPGVSVHLS VHSYFTVPDTRELPSIPENRNLTEY FVAVDVNNMLHLYASMLYERRILII CSKLSTLTACIHGSAAMLYPMYWQH VYIPVLPPHLLDYCCAPMPYLIGIH LSLMEKVRNMALDDVVILNVDTNTL ETPFDDLQSLPNDVISSLKNRLKKV STTTGDGVARAFLKAQAAFFGSYRN ALKIEPEEPITFCEEAFVSHYRSGA MRQFLQNATQLQLFKQFIDGRLDLL NSGEGFSDVFEEEINMGEYAGSDKL YHQWLSTVRKGSGAILNTVKTKANP AMKTVYKFAKDHAKMGIKEVKNRLK QKDIAENGCAPTPEEQLPKTAPSPL VEAKDPKLREDRRPITVHFGQVRPP RPHVVKRPKSNIAVEGRRTSVPSPE QNTIATPATLHILQKSITHFAAKFP TRGWTSSSH |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | DENND1A DENN/MADD domain containing 1A [ Homo sapiens ] |
Official Symbol : | DENND1A |
Synonyms : | FAM31A; KIAA1608; RP11-230L22.3 |
Gene ID : | 57706 |
mRNA Refseq : | NM_024820.2 |
Protein Refseq : | NP_079096.2 |
MIM : | 613633 |
UniProt ID : | Q8TEH3 |
Products Types
◆ Recombinant Protein | ||
DENND1A-2324M | Recombinant Mouse DENND1A Protein, His (Fc)-Avi-tagged | +Inquiry |
DENND1A-1186H | Recombinant Human DENND1A Protein, His-SUMO-tagged | +Inquiry |
DENND1A-4505M | Recombinant Mouse DENND1A Protein | +Inquiry |
◆ Lysates | ||
DENND1A-6978HCL | Recombinant Human DENND1A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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