Recombinant Human DHPS Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | DHPS-5177H |
Product Overview : | DHPS MS Standard C13 and N15-labeled recombinant protein (NP_037539) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor, forming an intermediate deoxyhypusine residue. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 34.8 kDa |
AA Sequence : | MEGSLEREAPAGALAAVLKHSSTLP PESTQVRGYDFNRGVNYRALLEAFG TTGFQATNFGRAVQQVNAMIEKKLE PLSQDEDQHADLTQSRRPLTSCTIF LGYTSNLISSGIRETIRYLVQHNMV DVLVTTAGGVEEDLIKCLAPTYLGE FSLRGKELRENGINRIGNLLVPNEN YCKFEDWLMPILDQMVMEQNTEGVK WTPSKMIARLGKEINNPESVYYWAQ KNHIPVFSPALTDGSLGDMIFFHSY KNPGLVLDIVEGARPDEAVSWGKIR VDAQPVKVYADASLVFPLLVAETFA QKMDAFMHEKNEDTRTRPLEQKLIS EEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | DHPS deoxyhypusine synthase [ Homo sapiens (human) ] |
Official Symbol : | DHPS |
Synonyms : | DHPS; deoxyhypusine synthase; MIG13; migration inducing gene 13; migration-inducing gene 13; DS; DHS; |
Gene ID : | 1725 |
mRNA Refseq : | NM_013407 |
Protein Refseq : | NP_037539 |
MIM : | 600944 |
UniProt ID : | P49366 |
Products Types
◆ Recombinant Protein | ||
DHPS-2356M | Recombinant Mouse DHPS Protein, His (Fc)-Avi-tagged | +Inquiry |
DHPS-2592H | Recombinant Human DHPS Protein, GST-tagged | +Inquiry |
DHPS-1078R | Recombinant Rhesus Macaque DHPS Protein, His (Fc)-Avi-tagged | +Inquiry |
DHPS-1518R | Recombinant Rat DHPS Protein, His (Fc)-Avi-tagged | +Inquiry |
Dhps-2547M | Recombinant Mouse Dhps Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
DHPS-6942HCL | Recombinant Human DHPS 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, bacterial resistance to sulfonamides can arise due to mutations in DHPS that reduce the drug's binding affinity.
Yes, mutations in DHPS can lead to reduced effectiveness of sulfonamides, contributing to antibiotic resistance.
DHPS mutations have been associated with resistance to sulfadoxine-pyrimethamine, a drug used to prevent and treat malaria.
Sulfonamides are used to treat urinary tract infections, respiratory tract infections, and other bacterial infections.
DHPS has potential as a target for developing new antiparasitic drugs due to its role in folate biosynthesis in parasites such as Plasmodium.
Customer Reviews (3)
Write a reviewTheir expert team has been instrumental in addressing any challenges or concerns I have encountered during my experiments.
Their prompt and comprehensive assistance has proven invaluable in overcoming obstacles and optimizing my experimental protocols.
The DHPS protein boasts remarkable stability, allowing for extended storage without compromising its integrity or performance.
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