| Description : |
This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
25.8 kDa |
| Protein Length : |
266 |
| AA Sequence : |
MMALGAAGATRVFVAMVAAALGGHP LLGVSATLNSVLNSNAIKNLPPPLG GAAGHPGSAVSAAPGILYPGGNKYQ TIDNYQPYPCAEDEECGTDEYCASP TRGGDAGVQICLACRKRRKRCMRHA MCCPGNYCKNGICVSSDQNHFRGEI EETITESFGNDHSTLDGYSRRTTLS SKMYHTKGQEGSVCLRSSDCASGLC CARHFWSKICKPVLKEGQVCTKHRR KGSHGLEIFQRCYCGEGLSCRIQKD HHQASNSSRLHTCQRH |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
