Recombinant Human DKK3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: DKK3-813H
• Product Overview: DKK3 MS Standard C13 and N15-labeled recombinant protein (NP_056965) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 38.3 kDa
• AA Sequence: MQRLGATLLCLLLAAAVPTAPAPAP TATSAPVKPGPALSYPQEEATLNEM FREVEELMEDTQHKLRSAVEEMEAE EAAAKASSEVNLANLPPSYHNETNT DTKVGNNTIHVHREIHKITNNQTGQ MVFSETVITSVGDEEGRRSHECIID EDCGPSMYCQFASFQYTCQPCRGQR MLCTRDSECCGDQLCVWGHCTKMAT RGSNGTICDNQRDCQPGLCCAFQRG LLFPVCTPLPVEGELCHDPASRLLD LITWELEPDGALDRCPCASGLLCQP HSHSLVYVCKPTFVGSRDQDGEILL PREVPDEYEVGSFMEEVRQELEDLE RSLTEEMALGEPAAAAAALLGGEEI TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: DKK3 dickkopf WNT signaling pathway inhibitor 3 [ Homo sapiens (human) ]
• Official Symbol: DKK3
• Synonyms: DKK3; dickkopf 3 homolog (Xenopus laevis); dickkopf (Xenopus laevis) homolog 3; dickkopf-related protein 3; regulated in glioma; REIC; RIG; dkk-3; hDkk-3; dickkopf-3; RIG-like 5-6; RIG-like 7-1; dickkopf homolog 3
• Gene ID: 27122
• mRNA Refseq: NM_015881
• Protein Refseq: NP_056965
• MIM: 605416
• UniProt ID: Q9UBP4