Recombinant Human DLK1 Protein, GST-tagged

• Cat.No.: DLK1-2683H
• Product Overview: Human DLK1 full-length ORF ( AAH07741.1, 25 a.a. - 383 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal. [provided by RefSeq, Nov 2015]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 65.23 kDa
• AA Sequence: ECFPACNPQNGFCEDDNVCRCQPGW QGPLCDQCVTSPGCLHGLCGEPGQC ICTDGWDGELCDRDVRACSSAPCAN NGTCVSLDDGLYECSRAPGYSGKDC QKKDGPCVINGSPCQHGGTCVDDEG RASHASCLCPPGFSGNFCEIVANSC TPNPCENDGVCTDIGGDFRCRCPAG FIDKTCSRPVTNCASSPCQNGGTCL QHTQVSYECLCKPEFTGLTCVKKRA LSPQQVTRLPNGYGLAYRLTPGVHE LPVQQPEHRILKVSMKELNKKTPLL TEGQAICFTILGVLTSLVVLGTVGI VFLNKCETWVSNLRYNHMLRKKKNL LLQYNSGEDLAVNIIFPEKIDMTTF SKEAGDEEI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DLK1 delta-like 1 homolog (Drosophila) [ Homo sapiens ]
• Official Symbol: DLK1
• Synonyms: DLK1; delta-like 1 homolog (Drosophila); delta like homolog (Drosophila); protein delta homolog 1; Delta1; FA1; pG2; Pref 1; ZOG; DLK-1; secredeltin; fetal antigen 1; preadipocyte factor 1; DLK; PREF1; Pref-1
• Gene ID: 8788
• mRNA Refseq: NM_003836
• Protein Refseq: NP_003827
• MIM: 176290
• UniProt ID: P80370