Recombinant Human DMRT1
Cat.No. : | DMRT1-27093TH |
Product Overview : | Recombinant full length Human DMRT1 with N terminal proprietary tag; Predicted MWt 67.14 kDa. |
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Description : | This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. |
Protein length : | 373 amino acids |
Molecular Weight : | 67.140kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Testis specific. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MPNDEAFSKPSTPSEAPHAPGVPPQGRAGGFGKASGALVG AASGSSAGGSSRGGGSGSGASDLGAGSKKSPRLPKCARCR NHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVA LRRQQAQEEELGISHPIPLPSAAELLVKRENNGSNPCLMT ECSGTSQPPPASVPTTAASEGRMVIQDIPAVTSRGHVENT PDLVSDSTYYSSFYQPSLFPYYNNLYNCPQYSMALAADSA SGEVGNPLGGSPVKNSLRGLPGPYVPGQTGNQWQMKNMEN RHAMSSQYRMHSYYPPPSYLGQSVPQFFTFEDAPSYPEAR ASVFSPPSSQDSGLVSLSSSSPISNKSTKAVLECEPASEP SSFTVTPVIEEDE |
Sequence Similarities : | Belongs to the DMRT family.Contains 1 DM DNA-binding domain. |
Gene Name : | DMRT1 doublesex and mab-3 related transcription factor 1 [ Homo sapiens ] |
Official Symbol : | DMRT1 |
Synonyms : | DMRT1; doublesex and mab-3 related transcription factor 1; doublesex- and mab-3-related transcription factor 1; DM domain expressed in testis 1; DMT1; |
Gene ID : | 1761 |
mRNA Refseq : | NM_021951 |
Protein Refseq : | NP_068770 |
MIM : | 602424 |
Uniprot ID : | Q9Y5R6 |
Chromosome Location : | 9p24.3 |
Function : | metal ion binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; |
Products Types
◆ Recombinant Protein | ||
Dmrt1-2587M | Recombinant Mouse Dmrt1 Protein, Myc/DDK-tagged | +Inquiry |
DMRT1-2709H | Recombinant Human DMRT1 Protein, GST-tagged | +Inquiry |
DMRT1-2414M | Recombinant Mouse DMRT1 Protein, His (Fc)-Avi-tagged | +Inquiry |
DMRT1-4649M | Recombinant Mouse DMRT1 Protein | +Inquiry |
DMRT1-11775Z | Recombinant Zebrafish DMRT1 | +Inquiry |
◆ Lysates | ||
DMRT1-6898HCL | Recombinant Human DMRT1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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