Recombinant Human DnaJ (Hsp40) Homolog, Subfamily B, Member 1, His-tagged;
Cat.No. : | DNAJB1-323H |
Product Overview : | Recombinant human HSP40, his-tagged, is overexpressed in E.coli and purified by using the conventional column chromatography techniques (360 aa,40.2 kDa). |
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Cat. No. : | DNAJB1-323H |
Description : | Human HSP40 (heat shock protein with molecular size of 40kDa) is one of the mammalian homologues of bacterial DnaJ heat shock protein and regulates cellular processes by aiding in the folding, transport and assembly. HSP40 protein contains the J-domain which controls interaction with the ATPase domain of DnaK. |
Source : | E.coli. |
Formulation : | Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 2 mM DTT, 0.2 mM PMSF, 10% glycerol. |
Molecular Weight : | 40.2 kDa (360 aa). |
Purity : | > 95% by SDS – PAGE. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Endotoxin Level : | < 1.0 EU per 1 μg of protein (determined by LAL method). |
Sequence : | MGSSHHHHHH SSGLVPRGSH MGKDYYQTLG LARGASDEEI KRAYRRQALR YHPDKNKEPG AEEKFKEIAE AYDVLSDPRK REIFDRYGEE GLKGSGPSGG SGGGANGTSF SYTFHGDPHA MFAEFFGGRN PFDTFFGQRN GEEGMDIDDP FSGFPMGMGG FTNVNFGRSR SAQEPARKKQ DPPVTHDLRV SLEEIYSGCT KKMKISHKRL NPDGKSIRNE DKILTIEVKK GWKEGTKITF PKEGDQTSNN IPADIVFVLK DKPHNIFKRD GSDVIYPARI SLREALCGCT VNVPTLDGRT IPVVFKDVIR PGMRRKVPGE GLPLPKTPEK RGDLIIEFEV IFPERIPQTS RTVLEQVLPI |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | DNAJB1 |
Synonyms : | DNAJB1; DnaJ (Hsp40) homolog, subfamily B, member 1; Hdj1; Sis1; HSPF1; Hsp40; DNAJ1; HDJ-1; HDJ1; DnaJ protein homolog 1; Heat shock protein 40; Heat shock 40 kDa protein 1; heat shock 40kD protein 1; DnaJ (Hsp40) homolog, subfamily B, member 1; Hsp40 (heat shock protein 40 kD). |
Gene ID : | 3337 |
mRNA Refseq : | NM_006145.1 |
Protein Refseq : | NP_006136.1 |
MIM : | 604572 |
UniProt ID : | P25685 |
Chromosome Location : | 19p13.2 |
Function : | heat shock protein binding; unfolded protein binding. |
Products Types
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DNAJB1-036H | Recombinant Human DNAJB1 Protein, N-6×His-tagged | +Inquiry |
DNAJB1-774H | Recombinant Human DNAJB1 Protein, His (Fc)-Avi-tagged | +Inquiry |
DNAJB1-5389H | Recombinant Human DnaJ (Hsp40) Homolog, Subfamily B, Member 1 | +Inquiry |
◆ Lysates | ||
DNAJB1-6892HCL | Recombinant Human DNAJB1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionDNAJB1 plays a role in neurodegenerative diseases by influencing the handling of misfolded proteins in neurons.
DNAJB1 modulates the immune system, particularly in controlling inflammation and immune cell responses.
DNAJB1 aids in protein folding and prevents the aggregation of misfolded proteins, crucial for maintaining cellular proteostasis.
DNAJB1 regulates apoptosis and cell survival, especially under conditions of cellular stress.
DNAJB1 affects cancer cell behavior, influencing tumor growth, survival, and sensitivity to treatments.
DNAJB1 is key in cellular stress responses, particularly to heat shock, by stabilizing proteins and aiding in recovery.
Changes in DNAJB1 expression impact muscle cell function and health, potentially contributing to muscular disorders.
Customer Reviews (3)
Write a reviewEfficient peptide synthesis, crucial for advancing our peptide research.
Exceptional protein engineering services, a vital resource for our lab.
Reliable protein crystallography, a crucial part of structural research.
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