Recombinant Human DNAJB1 protein, His/MBP-tagged
Cat.No. : | DNAJB1-271H |
Product Overview : | Recombinant Human DNAJB1(176-333 aa) fused with His/MBP tag was expressed in E. coli. |
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Description : | This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in order to promote protein folding and prevent misfolded protein aggregation. Alternative splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Human |
Tag : | His/MBP |
Form : | Liquid in PBS |
Protein length : | 176-333 aa |
Purity : | SDS-PAGE >90% |
Applications : | WB Positive Control |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Gene Name : | DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 [ Homo sapiens ] |
Official Symbol : | DNAJB1 |
Synonyms : | DNAJB1; DnaJ (Hsp40) homolog, subfamily B, member 1; HSPF1; dnaJ homolog subfamily B member 1; Hsp40; radial spoke 16 homolog B (Chlamydomonas); RSPH16B; Sis1; hDj-1; human DnaJ protein 1; heat shock protein 40; dnaJ protein homolog 1; heat shock 40kD protein 1; radial spoke 16 homolog B; heat shock 40 kDa protein 1; DnaJ (Hsp40) homolog, subfmaily B, member 1; Hdj1; |
Gene ID : | 3337 |
mRNA Refseq : | NM_006145 |
Protein Refseq : | NP_006136 |
MIM : | 604572 |
UniProt ID : | P25685 |
Products Types
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DNAJB1-774H | Recombinant Human DNAJB1 Protein, His (Fc)-Avi-tagged | +Inquiry |
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DNAJB1-5389H | Recombinant Human DnaJ (Hsp40) Homolog, Subfamily B, Member 1 | +Inquiry |
◆ Lysates | ||
DNAJB1-6892HCL | Recombinant Human DNAJB1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionDNAJB1 plays a role in neurodegenerative diseases by influencing the handling of misfolded proteins in neurons.
DNAJB1 modulates the immune system, particularly in controlling inflammation and immune cell responses.
DNAJB1 aids in protein folding and prevents the aggregation of misfolded proteins, crucial for maintaining cellular proteostasis.
DNAJB1 regulates apoptosis and cell survival, especially under conditions of cellular stress.
DNAJB1 affects cancer cell behavior, influencing tumor growth, survival, and sensitivity to treatments.
DNAJB1 is key in cellular stress responses, particularly to heat shock, by stabilizing proteins and aiding in recovery.
Changes in DNAJB1 expression impact muscle cell function and health, potentially contributing to muscular disorders.
Customer Reviews (3)
Write a reviewEfficient peptide synthesis, crucial for advancing our peptide research.
Exceptional protein engineering services, a vital resource for our lab.
Reliable protein crystallography, a crucial part of structural research.
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