Recombinant Human DPH5 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | DPH5-6497H |
Product Overview : | DPH5 MS Standard C13 and N15-labeled recombinant protein (NP_057042) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 31.5 kDa |
AA Sequence : | MLYLIGLGLGDAKDITVKGLEVVRR CSRVYLEAYTSVLTVGKEALEEFYG RKLVVADREEVEQEADNILKDADIS DVAFLVVGDPFGATTHSDLVLRATK LGIPYRVIHNASIMNAVGCCGLQLY KFGETVSIVFWTDTWRPESFFDKVK KNRQNGMHTLCLLDIKVKEQSLENL IKGRKIYEPPRYMSVNQAAQQLLEI VQNQRIRGEEPAVTEETLCVGLARV GADDQKIAAGTLRQMCTVDLGEPLH SLIITGGSIHPMEMEMLSLFSIPEN SSESQSINGLTRTRPLEQKLISEED LAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | DPH5 diphthamide biosynthesis 5 [ Homo sapiens (human) ] |
Official Symbol : | DPH5 |
Synonyms : | DPH5; DPH5 homolog (S. cerevisiae); diphthine synthase; CGI 30; protein x 0011; diphthamide biosynthesis methyltransferase; AD-018; CGI-30; NPD015; HSPC143; MGC61450; |
Gene ID : | 51611 |
mRNA Refseq : | NM_015958 |
Protein Refseq : | NP_057042 |
MIM : | 611075 |
UniProt ID : | Q9H2P9 |
Products Types
◆ Recombinant Protein | ||
DPH5-2501M | Recombinant Mouse DPH5 Protein, His (Fc)-Avi-tagged | +Inquiry |
DPH5-2835H | Recombinant Human DPH5 Protein, GST-tagged | +Inquiry |
DPH5-2477H | Recombinant Human DPH5 Protein, MYC/DDK-tagged | +Inquiry |
Dph5-2636M | Recombinant Mouse Dph5 Protein, Myc/DDK-tagged | +Inquiry |
DPH5-1145R | Recombinant Rhesus Macaque DPH5 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
DPH5-507HCL | Recombinant Human DPH5 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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