Recombinant Human DRD2 protein, His&Flag-tagged

• Cat.No.: DRD2-1099HFL
• Product Overview: Recombinant Full Length Human DRD2 protein(NP_000786)(1-443 aa), fused with His and Flag tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: His&Flag
• Form: Lyophilized from a 0.2 μm filtered solution in PBS, pH7.4 with 10% glycerin as protectant.
• Protein length: 1-443 aa
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied; 1 month, 2 to 8 °C under sterile conditions after reconstitution; 3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Reconstitution: It is recommended to reconstitute the lyophilized powder in sterile water to 100-200 ug/ml, and further dilute with other solvents.It can be stored at 4°C for 2-7 days and should be used up as soon as possible. If not in use for a short time, please store at -20°C.

Gene Information

• Gene Name: DRD2 dopamine receptor D2 [ Homo sapiens ]
• Official Symbol: DRD2
• Synonyms: DRD2; dopamine receptor D2; D(2) dopamine receptor; dopamine D2 receptor; dopamine receptor D2 isoform; seven transmembrane helix receptor; D2R; D2DR
• Gene ID: 1813
• mRNA Refseq: NM_000795
• Protein Refseq: NP_000786
• MIM: 126450
• UniProt ID: P14416

Reviews

01/10/2019

Integral to our research success, highly recommended.

03/26/2018

Efficiency at its best, a research cornerstone.

03/26/2018

Swift and accurate service, accelerates research timelines.

Q&As

What potential therapeutic applications arise from targeting DRD2 in neurological disorders?

Targeting DRD2 could treat disorders like Parkinson's and schizophrenia.

How do genetic variations in DRD2 affect behavior?

Genetic variations in DRD2 influence behavioral and mental health responses.

How does DRD2 contribute to motor control?

It regulates motor control via dopamine pathways.

How does DRD2 interact with other dopamine receptors?

DRD2 collaborates with other dopamine receptors in brain functions.

What is the primary role of DRD2 in neurotransmission?

DRD2 modulates neurotransmitter signaling in the brain.

What role does DRD2 play in psychiatric disorders?

DRD2 is key in psychiatric conditions, affecting mood and cognition.

What is the impact of altered DRD2 activity on addiction?

Altered DRD2 activity is linked to addiction, affecting reward mechanisms.