Recombinant Human DSG1 protein(50-609aa), His-tagged

• Cat.No.: DSG1-1794H
• Product Overview: Recombinant Human DSG1 protein(Q14126)(50-609aa), fused with N-terminal His tag, was expressed in E.coli.

Specification

• Source: E.coli
• Species: Human
• Tag: N-His
• Protein length: 50-609aa
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 68.4 kDa
• AASequence: AWITAPVALREGEDLSKKNPIAKIH SDLAEERGLKITYKYTGKGITEPPF GIFVFNKDTGELNVTSILDREETPF FLLTGYALDARGNNVEKPLELRIKV LDINDNEPVFTQDVFVGSVEELSAA HTLVMKINATDADEPNTLNSKISYR IVSLEPAYPPVFYLNKDTGEIYTTS VTLDREEHSSYTLTVEARDGNGEVT DKPVKQAQVQIRILDVNDNIPVVEN KVLEGMVEENQVNVEVTRIKVFDAD EIGSDNWLANFTFASGNEGGYFHIE TDAQTNEGIVTLIKEVDYEEMKNLD FSVIVANKAAFHKSIRSKYKPTPIP IKVKVKNVKEGIHFKSSVISIYVSE SMDRSSKGQIIGNFQAFDEDTGLPA HARYVKLEDRDNWISVDSVTSEIKL AKLPDFESRYVQNGTYTVKIVAISE DYPRKTITGTVLINVEDINDNCPTL IEPVQTICHDAEYVNVTAEDLDGHP NSGPFSFSVIDKPPGMAEKWKIARQ ESTSVLLQQSEKKLGRSEIQFLISD NQGFSCPEKQVLTLTVCECLHGSGC REAQHDSYVG
• Purity: Greater than 85% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C.

Gene Information

• Gene Name: DSG1 desmoglein 1 [ Homo sapiens ]
• Official Symbol: DSG1
• Synonyms: DSG1; desmoglein 1; DSG; desmoglein-1; CDHF4; DGI; cadherin family member 4; desmosomal glycoprotein 1; pemphigus foliaceus antigen; DG1; PPKS1; SPPK1
• Gene ID: 1828
• mRNA Refseq: NM_001942
• Protein Refseq: NP_001933
• MIM: 125670
• UniProt ID: Q02413

Reviews

02/22/2023

Its impeccable purity and integrity make it a valuable asset in my research endeavors.

03/02/2022

Their team of experts has been instrumental in resolving any queries or challenges I encountered regarding the application and utilization of the DSG1 protein.

03/22/2021

The DSG1 protein surpasses expectations in terms of quality and is an ideal match for my experimental requirements.

Q&As

How is DSG1 expression regulated in the skin?

Various factors, including cytokines and growth factors, can regulate the expression of DSG1 in skin cells.

Are there any clinical trials focused on DSG1 protein therapies?

Some clinical trials may be exploring DSG1-based therapies for skin disorders, but you should consult clinical trial databases for specific information.

What other medical conditions are associated with DSG1 protein?

DSG1 abnormalities are primarily linked to skin disorders, but some studies suggest potential connections to oral mucosa disorders.

Can DSG1 be used as a biomarker for skin cancer?

While DSG1 is not a direct biomarker for skin cancer, its expression levels may be altered in some skin cancers.

Can DSG1-targeted therapies be used to treat skin conditions?

Research is ongoing, but DSG1-targeted therapies have the potential to treat conditions related to DSG1 deficiencies.