Recombinant Human DSPP Protein, His&GST-tagged

• Cat.No.: DSPP-1390H
• Product Overview: Recombinant Human DSPP Protein (Gly82-Glu326) with N-His&GST tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family of proteins. The encoded preproprotein is secreted by odontoblasts and proteolytically processed to generate two principal proteins of the dentin extracellular matrix of the tooth, dentin sialoprotein and dentin phosphoprotein. These two protein products may play distinct but related roles in dentin mineralization. Mutations in this gene are associated with dentinogenesis imperfecta and dentin dysplasia. This gene is present in a gene cluster on chromosome 4. Allelic differences due to repeat polymorphisms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: N-His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 55.6 kDa
  Accurate Molecular Mass: 70 kDa
• Protein length: Gly82-Glu326
• Purity: > 80%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: DSPP dentin sialophosphoprotein [ Homo sapiens (human) ]
• Official Symbol: DSPP
• Synonyms: DSPP; dentin sialophosphoprotein; DPP; DSP; DGI1; DMP3; DFNA39; dentin sialophosphoprotein; deafness, autosomal dominant 39; dentin phosphophoryn; dentin phosphoprotein; dentin phosphoryn; dentin sialoprotein
• Gene ID: 1834
• mRNA Refseq: NM_014208
• Protein Refseq: NP_055023
• MIM: 125485
• UniProt ID: Q9NZW4