Recombinant Human DUSP9 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | DUSP9-5092H |
Product Overview : | DUSP9 MS Standard C13 and N15-labeled recombinant protein (NP_001386) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types. Alternate splicing results in multiple transcript variants. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 41.9 kDa |
AA Sequence : | MEGLGRSCLWLRRELSPPRPRLLLL DCRSRELYESARIGGALSVALPALL LRRLRRGSLSVRALLPGPPLQPPPP APVLLYDQGGGRRRRGEAEAEAEEW EAESVLGTLLQKLREEGYLAYYLQG GFSRFQAECPHLCETSLAGRAGSSM APLPGPVPVVGLGSLCLGSDCSDAE SEADRDSMSCGLDSEGATPPPVGLR ASFPVQILPNLYLGSARDSANLESL AKLGIRYILNVTPNLPNFFEKNGDF HYKQIPISDHWSQNLSRFFPEAIEF IDEALSQNRGVLVHCLAGVSRSVTV TVAYLMQKLHLSLNDAYDLVKRKKS NISPNFNFMGQLLDFERSLRLEERH SQEQGSGGQASAASNPPSFFTTPTS DGAFELAPTTRTRPLEQKLISEEDL AANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | DUSP9 dual specificity phosphatase 9 [ Homo sapiens (human) ] |
Official Symbol : | DUSP9 |
Synonyms : | DUSP9; dual specificity phosphatase 9; dual specificity protein phosphatase 9; map kinase phosphatase 4; MKP 4; MKP4; serine/threonine specific protein phosphatase; mitogen-activated protein kinase phosphatase 4; MKP-4; |
Gene ID : | 1852 |
mRNA Refseq : | NM_001395 |
Protein Refseq : | NP_001386 |
MIM : | 300134 |
UniProt ID : | Q99956 |
Products Types
◆ Recombinant Protein | ||
Dusp9-2692M | Recombinant Mouse Dusp9 Protein, Myc/DDK-tagged | +Inquiry |
DUSP9-1182R | Recombinant Rhesus Macaque DUSP9 Protein, His (Fc)-Avi-tagged | +Inquiry |
DUSP9-2948H | Recombinant Human DUSP9 Protein, GST-tagged | +Inquiry |
DUSP9-2010H | Recombinant Human DUSP9 Protein (Met1-Thr384), N-His tagged | +Inquiry |
DUSP9-12220H | Recombinant Human DUSP9, His-tagged | +Inquiry |
◆ Lysates | ||
DUSP9-6769HCL | Recombinant Human DUSP9 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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