Recombinant Human DVL2, GST-tagged
Cat.No. : | DVL2-107H |
Product Overview : | Recombinant Human DVL2(1 a.a. - 736 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. |
Source : | Wheat germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 105.3 kDa |
AA Sequence : | MAGSSTGGGGVGETKVIYHLDEEET PYLVKIPVPAERITLGDFKSVLQRP AGAKYFFKSMDQDFGVVKEEISDDN ARLPCFNGRVVSWLVSSDNPQPEMA PPVHEPRAELAPPAPPLPPLPPERT SGIGDSRPPSFHPNVSSSHENLEPE TETESVVSLRRERPRRRDSSEHGAG GHRTGGPSRLERHLAGYESSSTLMT SELESTSLGDSDEEDTMSRFSSSTE QSSASRLLKRHRRRRKQRPPRLERT SSFSSVTDSTMSLNIITVTLNMEKY NFLGISIVGQSNERGDGGIYIGSIM KGGAVAADGRIEPGDMLLQVNDMNF ENMSNDDAVRVLRDIVHKPGPIVLT VAKCWDPSPQAYFTLPRNEPIQPID PAAWVSHSAALTGTFPAYPGSSSMS TITSGSSLPDGCEGRGLSVHTDMAS VTKAMAAPESGLEVRDRMWLKITIP NAFLGSDVVDWLYHHVEGFPERREA RKYASGLLKAGLIRHTVNKITFSEQ CYYVFGDLSGGCESYLVNLSLNDND GSSGASDQDTLAPLPGATPWPLLPT FSYQYPAPHPYSPQPPPYHELSSYT YGGGSASSQHSEGSRSSGSTRSDGG AGRTGRPEERAPESKSGSGSESEPS SRGGSLRRGGEASGTSDGGPPPSRG STGGAPNLRAHPGLHPYGPPPGMAL PYNPMMVVMMPPPPPPVPPAVQPPG APPVRDLGSVPPELTASRQSFHMAM GNPSEFFVDVM |
Applications : | ELISA; WB-Re; AP; Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | DVL2 dishevelled, dsh homolog 2 (Drosophila) [ Homo sapiens ] |
Official Symbol : | DVL2 |
Synonyms : | DVL2; dishevelled, dsh homolog 2 (Drosophila); dishevelled 2 (homologous to Drosophila dsh); segment polarity protein dishevelled homolog DVL-2; dishevelled 2 (homologous to Drosophila dsh); Dishevelled dsh homolog 2; Dishevelled-2; Dishevelled2; DSH homolog 2; DVL 2; Dvl2; DVL2_HUMAN; Segment polarity protein dishevelled homolog DVL 2; Segment polarity protein dishevelled homolog DVL-2; Segment polarity protein dishevelled homolog DVL2; DSH homolog 2; dishevelled-2; OTTHUMP00000128349 |
Gene ID : | 1856 |
mRNA Refseq : | NM_004422 |
Protein Refseq : | NP_004413 |
MIM : | 602151 |
UniProt ID : | O14641 |
Chromosome Location : | 17p13.1 |
Pathway : | Basal cell carcinoma; Canonical Wnt signaling pathway; DNA damage response (only ATM dependent) |
Function : | frizzled binding; identical protein binding; protein binding; protein domain specific binding; protein self-association |
Products Types
◆ Recombinant Protein | ||
DVL2-2575M | Recombinant Mouse DVL2 Protein, His (Fc)-Avi-tagged | +Inquiry |
DVL2-1183R | Recombinant Rhesus Macaque DVL2 Protein, His (Fc)-Avi-tagged | +Inquiry |
DVL2-1358R | Recombinant Rhesus monkey DVL2 Protein, His-tagged | +Inquiry |
DVL2-1844H | Recombinant Human DVL2 protein, His-tagged | +Inquiry |
DVL2-11925Z | Recombinant Zebrafish DVL2 | +Inquiry |
◆ Lysates | ||
DVL2-6765HCL | Recombinant Human DVL2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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