Recombinant Human E2F1 Protein (Val88-Phe437), N-His tagged
Cat.No. : | E2F1-2016H |
Product Overview : | Recombinant human E2F1 (Val88-Phe437) fused with N-terminal His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters. Positively regulates transcription of RRP1B. |
Source : | E. coli |
Species : | Human |
Tag : | N-His |
Form : | Lyophilized powder/frozen liquid |
Molecular Mass : | 40.93 kDa |
Protein Length : | Val88-Phe437 |
Purity : | >90% as determined by SDS-PAGE |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Lyophilized from PBS, pH 7.4, 0.02% NLS, 1mM EDTA, 4% trehalose, 1% mannitol. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | E2F1 E2F transcription factor 1 [ Homo sapiens (human) ] |
Official Symbol : | E2F1 |
Synonyms : | E2F1; E2F transcription factor 1; RBBP3; transcription factor E2F1; RBP3; PBR3; RBAP-1; RBBP-3; PRB-binding protein E2F-1; retinoblastoma-binding protein 3; retinoblastoma-associated protein 1; E2F-1; RBAP1; |
Gene ID : | 1869 |
mRNA Refseq : | NM_005225 |
Protein Refseq : | NP_005216 |
MIM : | 189971 |
UniProt ID : | Q01094 |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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