| Description : |
The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
87 kDa |
| AA Sequence : |
MRGVWPPPVSALLSALGMSTYKRAT LDEEDLVDSLSEGDAYPNGLQVNFH SPRSGQRCWAARTQVEKRLVVLVVL LAAGLVACLAALGIQYQTRSPSVCL SEACVSVTSSILSSMDPTVDPCHDF FSYACGGWIKANPVPDGHSRWGTFS NLWEHNQAIIKHLLENSTASVSEAE RKAQVYYRACMNETRIEELRAKPLM ELIERLGGWNITGPWAKDNFQDTLQ VVTAHYRTSPFFSVYVSADSKNSNS NVIQVDQSGLGLPSRDYYLNKTENE KVLTGYLNYMVQLGKLLGGGDEEAI RPQMQQILDFETALANITIPQEKRR DEELIYHKVTAAELQTLAPAINWLP FLNTIFYPVEINESEPIVVYDKEYL EQISTLINTTDRCLLNNYMIWNLVR KTSSFLDQRFQDADEKFMEVMYGTK KTCLPRWKFCVSDTENNLGFALGPM FVKATFAEDSKSIATEIILEIKKAF EESLSTLKWMDEETRKSAKEKADAI YNMIGYPNFIMDPKELDKVFNDYTA VPDLYFENAMRFFNFSWRVTADQLR KAPNRDQWSMTPPMVNAYYSPTKNE IVFPAGILQAPFYTRSSPKALNFGG IGVVVGHELTHAFDDQGREYDKDGN LRPWWKNSSVEAFKRQTECMVEQYS NYSVNGEPVNGRHTLGENIADNGGL KAAYRAYQNWVKKNGAEHSLPTLGL TNNQLFFLGFAQVWCSVRTPESSHE GLITDPHSPSRFRVIGSLSNSKEFS EHFRCPPGSPMNPPHKCEVWTRTRP LEQKLISEEDLAANDILDYKDDDDK V |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
