Recombinant Human EDC3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: EDC3-3501H
• Product Overview: EDC3 MS Standard C13 and N15-labeled recombinant protein (NP_001135916) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 56.1 kDa
• AA Sequence: MATDWLGSIVSINCGDSLGVYQGRV SAVDQVSQTISLTRPFHNGVKCLVP EVTFRAGDITELKILEIPGPGDNQH FGDLHQTELGPSGAGCQVGINQNGT GKFVKKPASSSSAPQNIPKRTDVKS QDVAVSPQQQQCSKSYVDRHMESLS QSKSFRRRHNSWSSSSRHPNQATPK KSGLKNGQMKNKDDECFGDDIEEIP DTDFDFEGNLALFDKAAVFEEIDTY ERRSGTRSRGIPNERPTRYRHDENI LESEPIVYRRIIVPHNVSKEFCTDS GLVVPSISYELHKKLLSVAEKHGLT LERRLEMTGVCASQMALTLLGGPNR LNPKNVHQRPTVALLCGPHVKGAQG ISCGRHLANHDVQVILFLPNFVKML ESITNELSLFSKTQGQQVSSLKDLP TSPVDLVINCLDCPENVFLRDQPWY KAAVAWANQNRAPVLSIDPPVHEVE QGIDAKWSLALGLPLPLGEHAGRIY LCDIGIPQQVFQEVGINYHSPFGCK FVIPLHSATRTRPLEQKLISEEDLA ANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: EDC3 enhancer of mRNA decapping 3 [ Homo sapiens (human) ]
• Official Symbol: EDC3
• Synonyms: EDC3; enhancer of mRNA decapping 3 homolog (S. cerevisiae); LSM16, LSM16 homolog (EDC3, S. cerevisiae), YJDC, yjeF domain containing (E.coli); enhancer of mRNA-decapping protein 3; FLJ21128; hYjeF_N2 15q23; YJEFN2; yjeF_N2; hYjeF_N2; hYjeF_N2-15q23; yjeF domain containing; yjeF domain-containing protein 1; LSM16 homolog (EDC3, S. cerevisiae); yjeF N-terminal domain-containing protein 2; YJDC; LSM16; FLJ31777
• Gene ID: 80153
• mRNA Refseq: NM_001142444
• Protein Refseq: NP_001135916
• MIM: 609842
• UniProt ID: Q96F86