Recombinant Human EDNRB
Cat.No. : | EDNRB-28559TH |
Product Overview : | Recombinant fragment of Human Endothelin B Receptor with a N terminal proprietary tag: predicted molecular weight 33.88 kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Protein length : | 75 amino acids |
Molecular Weight : | 33.880kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Expressed in placental stem villi vessels, but not in cultured placental villi smooth muscle cells. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | EERGFPPDRATPLLQTAEIMTPPTK TLWPKGSNASLARSLAPAEVPKGDR TAGSPPRTISPPPCQGPIEIKETFK |
Sequence Similarities : | Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRB sub-subfamily. |
Gene Name : | EDNRB endothelin receptor type B [ Homo sapiens ] |
Official Symbol : | EDNRB |
Synonyms : | EDNRB; endothelin receptor type B; HSCR, HSCR2; endothelin B receptor; ETB; |
Gene ID : | 1910 |
mRNA Refseq : | NM_000115 |
Protein Refseq : | NP_000106 |
MIM : | 131244 |
Uniprot ID : | P24530 |
Chromosome Location : | 13q22 |
Pathway : | Arf6 trafficking events, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Endothelins, organism-specific biosystem; |
Function : | G-protein coupled receptor activity; endothelin receptor activity; endothelin receptor activity; endothelin receptor activity; peptide hormone binding; |
Products Types
◆ Recombinant Protein | ||
EDNRB-3061H | Recombinant Human EDNRB Protein, GST-tagged | +Inquiry |
EDNRB-2642M | Recombinant Mouse EDNRB Protein, His (Fc)-Avi-tagged | +Inquiry |
EDNRB-1209H | Recombinant Human EDNRB Protein, MYC/DDK-tagged | +Inquiry |
EDNRB-1669R | Recombinant Rat EDNRB Protein, His (Fc)-Avi-tagged | +Inquiry |
Ednrb-2730M | Recombinant Mouse Ednrb Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
EDNRB-001HCL | Recombinant Human EDNRB cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1230 | EDNRB CHO-K1 β-Arrestin GPCR Assay Kit | +Inquiry |
Kit-1231 | EDNRB Total GPCR Internalization Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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