Recombinant Human EFS Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: EFS-3849H
• Product Overview: EFS MS Standard C13 and N15-labeled recombinant protein (NP_115835) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The longest protein isoform encoded by this gene contains an SH3 domain, which is known to be important in intracellular signal transduction. The protein encoded by a similiar gene in mice was shown to bind to SH3 domains of protein-tyrosine kinases. The function of this gene is unknown. Three alternatively spliced variants encoding different isoforms have been described for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 49 kDa
• AA Sequence: MAIATSVYVVPPPARPCPTSGPPAG PCPPSPDLIYKIPRASGTQLAAPRD ALEVYDVPPTALRVPSSGPYDCPAS FSHPLTRVAPQPPGEDDAPYDVPLT PKPPAELEPDLEWEGGREPGPPIYA APSNLKRASALLNLYEAPEELLADG EGGGTDEGIYDVPLLGPEAPPSPEP PGALASHDQDTLAQLLARSPPPPHR PRLPSAESLSRRPLPALPVPEAPSP SPVPSPAPGRKGSIQDRPLPPPPPR LPGYGGPKVEGDPEGREMEDDPAGH HNEYEGIPMAEEYDYVHLKGMDKAQ GSRPPDQACTGDPELPERGMPAPQE ALSPGEPLVVSTGDLQLLYFYAGQC QSHYSALQAAVAALMSSTQANQPPR LFVPHSKRVVVAAHRLVFVGDTLGR LAASAPLRAQVRAAGTALGQALRAT VLAVKGAALGYPSSPAIQEMVQCVT ELAGQALQFTTLLTSLAPTRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: EFS embryonal Fyn-associated substrate [ Homo sapiens (human) ]
• Official Symbol: EFS
• Synonyms: EFS; embryonal Fyn-associated substrate; Cas scaffolding protein family member 3; CASS3; EFS1; EFS2; HEFS; SIN; signal transduction protein (SH3 containing); CAS3
• Gene ID: 10278
• mRNA Refseq: NM_032459
• Protein Refseq: NP_115835
• MIM: 609906
• UniProt ID: O43281