Recombinant Human EIF4A1 Protein (M1-I406), His/Strep tagged

• Cat.No.: EIF4A1-0102H
• Product Overview: Recombinant Human 6His-strepII-TEV-GG-EIF4A1(M1-I406 end) Protein was expressed in E. coli.

Specification

• Description: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
• Source: E. coli
• Species: Human
• Tag: His/Strep
• Form: Liquid
• Protein Length: M1-I406
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: EIF4A1 eukaryotic translation initiation factor 4A1 [ Homo sapiens (human) ]
• Official Symbol: EIF4A1
• Synonyms: EIF4A1; eukaryotic translation initiation factor 4A1; EIF4A, eukaryotic translation initiation factor 4A, isoform 1; eukaryotic initiation factor 4A-I; DDX2A; EIF 4A; eukaryotic initiation factor 4AI; ATP-dependent RNA helicase eIF4A-1; eukaryotic translation initiation factor 4A, isoform 1; EIF4A; EIF-4A; eIF4A-I; eIF-4A-I
• Gene ID: 1973
• mRNA Refseq: NM_001204510
• Protein Refseq: NP_001191439
• MIM: 602641
• UniProt ID: P60842