| Description : |
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
108.7 kDa |
| AA Sequence : |
MDGFAGSLDDSISAASTSDVQDRLS ALESRVQQQEDEITVLKAALADVLR RLAISEDHVASVKKSVSSKGQPSPR AVIPMSCITNGSGANRKPSHTSAVS IAGKETLSSAAKSGTEKKKEKPQGQ REKKEESHSNDQSPQIRASPSPQPS SQPLQIHRQTPESKNATPTKSIKRP SPAEKSHNSWENSDDSRNKLSKIPS TPKLIPKVTKTADKHKDVIINQEGE YIKMFMRGRPITMFIPSDVDNYDDI RTELPPEKLKLEWAYGYRGKDCRAN VYLLPTGEIVYFIASVVVLFNYEER TQRHYLGHTDCVKCLAIHPDKIRIA TGQIAGVDKDGRPLQPHVRVWDSVT LSTLQIIGLGTFERGVGCLDFSKAD SGVHLCVIDDSNEHMLTVWDWQKKA KGAEIKTTNEVVLAVEFHPTDANTI ITCGKSHIFFWTWSGNSLTRKQGIF GKYEKPKFVQCLAFLGNGDVLTGDS GGVMLIWSKTTVEPTPGKGPKGVYQ ISKQIKAHDGSVFTLCQMRNGMLLT GGGKDRKIILWDHDLNPEREIEVPD QYGTIRAVAEGKADQFLVGTSRNFI LRGTFNDGFQIEVQGHTDELWGLAT HPFKDLLLTCAQDRQVCLWNSMEHR LEWTRLVDEPGHCADFHPSGTVVAI GTHSGRWFVLDAETRDLVSIHTDGN EQLSVMRYSIDGTFLAVGSHDNFIY LYVVSENGRKYSRYGRCTGHSSYIT HLDWSPDNKYIMSNSGDYEILYWDI PNGCKLIRNRSDCKDIDWTTYTCVL GFQVFGVWPEGSDGTDINALVRSHN RKVIAVADDFCKVHLFQYPCSKAKA PSHKYSAHSSHVTNVSFTHNDSHLI STGGKDMSIIQWKLVEKLSLPQNET VADTTLTKAPVSSTESVIQSNTPTP PPSQPLNETAEEESRISSSPTLLEN SLEQTVEPSEDHSEEESEEGSGDLG EPLYEEPCNEISKEQAKATLLEDQQ DPSPSSTRTRPLEQKLISEEDLAAN DILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
