| Description : |
The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. |
| Source : |
HEK293 |
| Species : |
Human |
| Form : |
Lyophilized |
| Molecular Mass : |
94.5 kDa |
| Protein Length : |
863 |
| AA Sequence : |
MARRSSFQSCQIISLFTFAVGVNIC LGFTAHRIKRAEGWEEGPPTVLSDS PWTNISGSCKGRCFELQEAGPPDCR CDNLCKSYTSCCHDFDELCLKTARG WECTKDRCGEVRNEENACHCSEDCL ARGDCCTNYQVVCKGESHWVDDDCE EIKAAECPAGFVRPPLIIFSVDGFR ASYMKKGSKVMPNIEKLRSCGTHSP YMRPVYPTKTFPNLYTLATGLYPES HGIVGNSMYDPVFDATFHLRGREKF NHRWWGGQPLWITATKQGVKAGTFF WSVVIPHERRILTILQWLTLPDHER PSVYAFYSEQPDFSGHKYGPFGPEM TNPLREIDKIVGQLMDGLKQLKLHR CVNVIFVGDHGMEDVTCDRTEFLSN YLTNVDDITLVPGTLGRIRSKFSNN AKYDPKAIIANLTCKKPDQHFKPYL KQHLPKRLHYANNRRIEDIHLLVER RWHVARKPLDVYKKPSGKCFFQGDH GFDNKVNSMQTVFVGYGSTFKYKTK VPPFENIELYNVMCDLLGLKPAPNN GTHGSLNHLLRTNTFRPTMPEEVTR PNYPGIMYLQSDFDLGCTCDDKVEP KNKLDELNKRLHTKGSTEERHLLYG RPAVLYRTRYDILYHTDFESGYSEI FLMPLWTSYTVSKQAEVSSVPDHLT SCVRPDVRVSPSFSQNCLAYKNDKQ MSYGFLFPPYLSSSPEAKYDAFLVT NMVPMYPAFKRVWNYFQRVLVKKYA SERNGVNVISGPIFDYDYDGLHDTE DKIKQYVEGSSIPVPTHYYSIITSC LDFTQPADKCDGPLSVSSFILPHRP DNEESCNSSEDESKWVEELMKMHTA RVRDIEHLTSLDFFRKTSRSYPEIL TLKTYLHTYESEI |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
