Recombinant Human ENTPD4, His-tagged

• Cat.No.: ENTPD4-12469H
• Product Overview: Recombinant Human ENTPD4 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: This gene encodes a member of the apyrase protein family. Apyrases are enzymes that catalyze the hydrolysis of nucleotide diphosphates and triphosphates in a calcium or magnesium-dependent manner. The encoded protein is an endo-apyrase and may play a role in salvaging nucleotides from lysosomes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and these isoforms may differ in divalent cation dependence and substrate specificity.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: C-term-349a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 [ Homo sapiens ]
• Official Symbol: ENTPD4
• Synonyms: ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4; LYSAL1, lysosomal apyrase like 1; KIAA0392; LALP70; LAP70; NTPDase 4; UDPase; golgi luminal UDPase; uridine-diphosphatase; lysosomal apyrase-like 1; guanosine-diphosphatase like protein; lysosomal apyrase-like protein of 70 kDa; LYSAL1; NTPDase-4
• Gene ID: 9583
• mRNA Refseq: NM_001128930
• Protein Refseq: NP_001122402
• MIM: 607577
• UniProt ID: Q9Y227
• Chromosome Location: 8p21.3
• Pathway: Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem; Pyrimidine metabolism, organism-specific biosystem; Pyrimidine metabolism, conserved biosystem
• Function: hydrolase activity; uridine-diphosphatase activity