| Description : |
The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
71.8 kDa |
| AA Sequence : |
MHCKVSLLDDTVYECVVEKHAKGQD LLKRVCEHLNLLEEDYFGLAIWDNA TSKTWLDSAKEIKKQVRGVPWNFTF NVKFYPPDPAQLTEDITRYYLCLQL RQDIVAGRLPCSFATLALLGSYTIQ SELGDYDPELHGVDYVSDFKLAPNQ TKELEEKVMELHKSYRSMTPAQADL EFLENAKKLSMYGVDLHKAKDLEGV DIILGVCSSGLLVYKDKLRINRFPW PKVLKISYKRSSFFIKIRPGEQEQY ESTIGFKLPSYRAAKKLWKVCVEHH TFFRLTSTDTIPKSKFLALGSKFRY SGRTQAQTRQASALIDRPAPHFERT ASKRASRSLDGAAAVDSADRSPRPT SAPAITQGQVAEGGVLDASAKKTVV PKAQKETVKAEVKKEDEPPEQAEPE PTEAWKVEKTHIEVTVPTSNGDQTQ KKRERLDGENIYIRHSNLMLEDLDK SQEEIKKHHASISELKKNFMESVPE PRPSEWDKRLSTHSPFRTLNINGQI PTGEGPPLVKTQTVTISDNANAVKS EIPTKDVPIVHTETKTITYEAAQTD DNSGDLDPGVLLTAQTITSETPSST TTTQITKTVKGGISETRIEKRIVIT GDADIDHDQVLVQAIKEAKEQHPDM SVTKVVVHQETEIADETRTRPLEQK LISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
