Recombinant Human EPH Receptor A2, GST-tagged, Active
Cat.No. : | EPHA2-300H |
Product Overview : | Recombinant human EPHA2 (561-end) was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW=72kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | EPHA2-300H |
Description : | EPHA2 is a member of the ephrin receptor subfamily of protein-tyrosine kinases that bind the ephrin-A ligand and have diverse cellular function. EPHA2 has been shown to be an oncoprotein of importance in a range of cancers. EPHA2 is overexpressed in several human cancer types and promotes malignancy through a mechanism involving RhoA-dependent destabilization of adherens junctions. EPHA2 overexpression induces a FAK-dependent increase in MMP-2 expression and invasiveness and this process that can be reversed by ligation of EPHA2. |
Source : | Sf9 insect cellsusing baculovirus. |
Sequence : | 561-end. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | EPHA2 EPH receptor A2 [ Homo sapiens ] |
Synonyms : | EPHA2; EPH receptor A2; ECK; ARCC2; protein tyrosine kinase; soluble EPHA2 variant 1; soluble EPHA2 variant 1; epithelial cell receptor protein tyrosine kinase; ephrin receptor EphA2; EC 2.7.10.1 |
Gene ID : | 1969 |
mRNA Refseq : | NM_004431 |
Protein Refseq : | NP_004422 |
MIM : | 176946 |
UniProt ID : | P29317 |
Chromosome Location : | 1p36 |
Pathway : | Axon guidance |
Function : | ATP binding; ephrin receptor activity; nucleotide binding; protein binding; receptor activity; transferase activity |
Products Types
◆ Recombinant Protein | ||
EPHA2-0986H | Recombinant Human EPHA2 Protein (R561-I976), GST tagged | +Inquiry |
EPHA2-0985H | Recombinant Human EPHA2 Protein (R561-I976), Tag Free | +Inquiry |
Epha2-954M | Recombinant Mouse Epha2 Protein, MYC/DDK-tagged | +Inquiry |
Epha2-38M | Recombinant Mouse Epha2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Epha2-915MB | Recombinant Mouse Epha2 protein(Met1-Asn535), His & Avi-tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
EPHA2-2138MCL | Recombinant Mouse EPHA2 cell lysate | +Inquiry |
EPHA2-1072HCL | Recombinant Human EPHA2 cell lysate | +Inquiry |
EPHA2-001HCL | Recombinant Human EPHA2 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0326 | EphA2 Kinase (Human) Assay/Inhibitor Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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