Recombinant Human EPHX1, MYC/DDK-tagged

• Cat.No.: EPHX1-390H
• Product Overview: Recombinant Human EPHX1, fused with C-terminal MYC/DDK, was expressed in HEK293 Cells.

Specification

• Description: Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
• Source: HEK293 Cells
• Species: Human
• Tag: MYC/DDK
• Molecular Mass: 52.8 kDa
• Endotoxin: < 0.1 eu per 1 μg of the protein by the
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Storage: Store at -80 °C. Avoid repeated freeze-thaw cycles.
• Concentration: >50 ug/ml as determined by BCA
• Storage Buffer: 10% glycerol, 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) [ Homo sapiens ]
• Official Symbol: EPHX1
• Synonyms: EPHX1; epoxide hydrolase 1, microsomal (xenobiotic); EPHX; epoxide hydrolase 1; epoxide hydratase; MEH; EPOX; HYL1
• Gene ID: 2052
• mRNA Refseq: NM_000120
• Protein Refseq: NP_000111
• UniProt ID: P07099
• Chromosome Location: 1q42.1
• Pathway: Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Metabolism of xenobiotics by cytochrome P450, organism-specific biosystem; Metabolism of xenobiotics by cytochrome P450, conserved biosystem
• Function: cis-stilbene-oxide hydrolase activity; epoxide hydrolase activity; hydrolase activity