Recombinant Human ERCC5 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | ERCC5-6126H |
Product Overview : | ERCC5 MS Standard C13 and N15-labeled recombinant protein (NP_000114) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
- Download
Description : | This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, cognitive disability, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 133.3 kDa |
AA Sequence : | MGVQGLWKLLECSGRQVSPEALEGK ILAVDISIWLNQALKGVRDRHGNSI ENPHLLTLFHRLCKLLFFRIRPIFV FDGDAPLLKKQTLVKRRQRKDLASS DSRKTTEKLLKTFLKRQAIKTAFRS KRDEALPSLTQVRRENDLYVLPPLQ EEEKHSSEEEDEKEWQERMNQKQAL QEEFFHNPQAIDIESEDFSSLPPEV KHEILTDMKEFTKRRRTLFEAMPEE SDDFSQYQLKGLLKKNYLNQHIEHV QKEMNQQHSGHIRRQYEDEGGFLKE VESRRVVSEDTSHYILIKGIQAKTV AEVDSESLPSSSKMHGMSFDVKSSP CEKLKTEKEPDATPPSPRTLLAMQA ALLGSSSEEELESENRRQARGRNAP AAVDEGSISPRTLSAIKRALDDDED VKVCAGDDVQTGGPGAEEMRINSST ENSDEGLKVRDGKGIPFTATLASSS VNSAEEHVASTNEGREPTDSVPKEQ MSLVHVGTEAFPISDESMIKDRKDR LPLESAVVRHSDAPGLPNGRELTPA SPTCTNSVSKNETHAEVLEQQNELC PYESKFDSSLLSSDDETKCKPNSAS EVIGPVSLQETSSIVSVPSEAVDNV ENVVSFNAKEHENFLETIQEQQTTE SAGQDLISIPKAVEPMEIDSEESES DGSFIEVQSVISDEELQAEFPETSK PPSEQGEEELVGTREGEAPAESESL LRDNSERDDVDGEPQEAEKDAEDSL HEWQDINLEELETLESNLLAQQNSL KAQKQQQERIAATVTGQMFLESQEL LRLFGIPYIQAPMEAEAQCAILDLT DQTSGTITDDSDIWLFGARHVYRNF FNKNKFVEYYQYVDFHNQLGLDRNK LINLAYLLGSDYTEGIPTVGCVTAM EILNEFPGHGLEPLLKFSEWWHEAQ KNPKIRPNPHDTKVKKKLRTLQLTP GFPNPAVAEAYLKPVVDDSKGSFLW GKPDLDKIREFCQRYFGWNRTKTDE SLFPVLKQLDAQQTQLRIDSFFRLA QQEKEDAKRIKSQRLNRAVTCMLRK EKEAAASEIEAVSVAMEKEFELLDK AKRKTQKRGITNTLEESSSLKRKRL SDSKRKNTCGGFLGETCLSESSDGS SSEDAESSSLMNVQRRTAAKEPKTS ASDSQNSVKEAPVKNGGATTSSSSD SDDDGGKEKMVLVTARSVFGKKRRK LRRARGRKRKTTRTRPLEQKLISEE DLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | ERCC5 ERCC excision repair 5, endonuclease [ Homo sapiens (human) ] |
Official Symbol : | ERCC5 |
Synonyms : | ERCC5; excision repair cross-complementing rodent repair deficiency, complementation group 5; ERCM2, xeroderma pigmentosum, complementation group G, XPGC; DNA repair protein complementing XP-G cells; Cockayne syndrome; XPG-complementing protein; DNA excision repair protein ERCC-5; xeroderma pigmentosum, complementation group G; XPG; UVDR; XPGC; COFS3; ERCM2; |
Gene ID : | 2073 |
mRNA Refseq : | NM_000123 |
Protein Refseq : | NP_000114 |
MIM : | 133530 |
UniProt ID : | P28715 |
Products Types
◆ Recombinant Protein | ||
ERCC5-862H | Recombinant Human ERCC5 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ercc5-2854M | Recombinant Mouse Ercc5 Protein, Myc/DDK-tagged | +Inquiry |
ERCC5-3281C | Recombinant Chicken ERCC5 | +Inquiry |
ERCC5-2868H | Recombinant Human ERCC5 protein, His-tagged | +Inquiry |
ERCC5-2298H | Recombinant Human ERCC5 Protein (Leu778-Ala986), His tagged | +Inquiry |
◆ Lysates | ||
ERCC5-6563HCL | Recombinant Human ERCC5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All ERCC5 Products
Required fields are marked with *
My Review for All ERCC5 Products
Required fields are marked with *
0
Inquiry Basket