Recombinant Human EREG
Cat.No. : | EREG-28692TH |
Product Overview : | Recombinant full length mature Human EREG with N terminal Methionine; 50aa, 6kDa. |
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Description : | Epiregulin is a member of the epidermal growth factor family. Epiregulin can function as a ligand of EGFR (epidermal growth factor receptor), as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. |
Protein length : | 49 amino acids |
Molecular Weight : | 6.000kDa |
Source : | E. coli |
Tissue specificity : | In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon. |
Biological activity : | The ED50 was determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells is500,000 units/mg. |
Form : | Lyophilised:It is recommended to reconstitute in sterile Ultra pure water at not less than 100μg/ml, which can then be further diluted to other aqueous solutions. |
Purity : | by SDS-PAGE |
Storage buffer : | pH: 7.40Constituents:PBS, 0.76% Sodium chloride |
Storage : | Please see Notes section |
Sequences of amino acids : | MVAQVSITKCSSDMNGYCLHGQCIY LVDMSQNYCRCEVGYTGVRCEHFFL |
Sequence Similarities : | Contains 1 EGF-like domain. |
Gene Name : | EREG epiregulin [ Homo sapiens ] |
Official Symbol : | EREG |
Synonyms : | EREG; epiregulin; proepiregulin; ER; |
Gene ID : | 2069 |
mRNA Refseq : | NM_001432 |
Protein Refseq : | NP_001423 |
MIM : | 602061 |
Uniprot ID : | O14944 |
Chromosome Location : | 4q21.21 |
Pathway : | ErbB receptor signaling network, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, conserved biosystem; ErbB4 signaling events, organism-specific biosystem; |
Function : | epidermal growth factor receptor binding; epidermal growth factor receptor binding; growth factor activity; protein binding; |
Products Types
◆ Recombinant Protein | ||
EREG-023H | Active Recombinant Human EREG Protein | +Inquiry |
EREG-3465H | Recombinant Human EREG Protein, GST-tagged | +Inquiry |
EREG-1438H | Recombinant Human EREG Protein, His-tagged | +Inquiry |
EREG-004H | Active Recombinant Human EREG Protein | +Inquiry |
EREG-125E | Active Recombinant Human EREG Protein (50 aa) | +Inquiry |
◆ Lysates | ||
EREG-1868HCL | Recombinant Human EREG cell lysate | +Inquiry |
EREG-1871MCL | Recombinant Mouse EREG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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