Recombinant Human ETV6 Protein, GST-tagged

• Cat.No.: ETV6-3540H
• Product Overview: Human ETV6 full-length ORF ( AAH43399, 1 a.a. - 452 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 75.46 kDa
• AA Sequence: MSETPAQCSIKQERISYTPPESPVP SYASSTPLHVPVPRALRMEEDSIRL PAHLRLQPIYWSRDDVAQWLKWAEN EFSLRPIDSNTFEMNGKALLLLTKE DFRYRSPHSGDVLYELLQHILKQRK PRILFSPFFHPGNSIHTQPEVILHQ NHEEDNCVQRTPRPSVDNVHHNPPT IELLHRSRSPITTNHRPSPDPEQRP LRSPLDNMIRRLSPAERAQGPRPHQ ENNHQESYPLSVSPMENNHCPASSE SHPKPSSPRQESTRVIQLMPSPIMH PLILNPRHSVDFKQSRLSEDGLHRE GKPINLSHREDLAYMNHIMVSVSPP EEHAMPIGRIADCRLLWDYVYQLLS DSRYENFIRWEDKESKIFRIVDPNG LARLWGNHKNRTNMTYEKMSRALRH YYKLNIIRKEPGQRLLFRFMKTPDE IMSGRTDRLEHLESQELDEQIYQED EC
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ETV6 ets variant 6 [ Homo sapiens ]
• Official Symbol: ETV6
• Synonyms: ETV6; ets variant 6; ets variant gene 6 (TEL oncogene); transcription factor ETV6; TEL; TEL oncogene; TEL1 oncogene; ETS-related protein Tel1; ETS translocation variant 6; TEL/ABL
• Gene ID: 2120
• mRNA Refseq: NM_001987
• Protein Refseq: NP_001978
• MIM: 600618
• UniProt ID: P41212