Recombinant Human Eukaryotic Translation Initiation Factor 6, T7-tagged

• Cat.No.: EIF6-2911H
• Product Overview: Recombinant Human EIF6 protein was expressed in E.coli with T7-tag at N-terminus. The molecular weight is26599 Da (245 aa).

Specification

• Cat. No.: EIF6-2911H
• Description: Eukaryotic translation initiation factor 6 (EIF6), also known as Integrin beta 4 binding protein (ITGB4BP), is a human gene. The protein encoded by EIF6 binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple transcript variants encoding several different isoforms have been found for this gene.
• Sequences of amino acids: 1-245 aa
• Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3.
• Purity: 95%

Gene Information

• Gene Name: EIF6 eukaryotic translation initiation factor 6[ Homo sapiens ]
• Synonyms: 2; b; gcn; EIF3A; p27BBP; ITGB4BP; b(2)gcn; EIF-6; p27(BBP); b(2)GCN homolog; B4 integrin interactor; p27 beta-4 integrin-binding protein; eukaryotic translation initiation factor 3A; CAB; OK/SW-cl.27
• Gene ID: 3692
• mRNA Refseq: NM_002212
• Protein Refseq: NP_002203
• MIM: 602912
• UniProt ID: P56537
• Chromosome Location: 20q12
• Function: protein binding; ribosome binding; translation initiation factor activity